Evidence map›Paper›PMID 34575417›Full record

ReviewPharmaceutics2021

Biomaterials for Soft Tissue Repair and Regeneration: A Focus on Italian Research in the Field.

Maria Cristina Bonferoni, Carla Caramella, Laura Catenacci, Bice Conti, Rossella Dorati, Franca Ferrari, Ida Genta, Tiziana Modena, Sara Perteghella, Silvia Rossi and 4 more

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. The Potential of Composite Cements for Wound Healing in Rats.Bioengineering (Basel, Switzerland) · 2024
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maria Cristina BonferoniDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-1194-9372
Carla CaramellaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-1261-1525
Laura CatenacciDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-6791-3785
Bice ContiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-0034-2815
Rossella DoratiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5774-9547
Franca FerrariDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-2548-5249
Ida GentaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5710-0588
Tiziana ModenaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.
Sara PerteghellaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0003-1128-7636
Silvia RossiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-9511-3857
Giuseppina SandriDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-6766-9321
Milena SorrentiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-8249-5761
Maria Luisa TorreDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-8062-6836
Giuseppe TripodoDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5462-5629

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue repair and regeneration is an interdisciplinary field focusing on developing bioactive substitutes aimed at restoring pristine functions of damaged, diseased tissues. Biomaterials, intended as those materials compatible with living tissues after in vivo administration, play a pivotal role in this area and they have been successfully studied and developed for several years. Namely, the researches focus on improving bio-inert biomaterials that well integrate in living tissues with no or minimal tissue response, or bioactive materials that influence biological response, stimulating new tissue re-growth. This review aims to gather and introduce, in the context of Italian scientific community, cutting-edge advancements in biomaterial science applied to tissue repair and regeneration. After introducing tissue repair and regeneration, the review focuses on biodegradable and biocompatible biomaterials such as collagen, polysaccharides, silk proteins, polyesters and their derivatives, characterized by the most promising outputs in biomedical science. Attention is pointed out also to those biomaterials exerting peculiar activities, e.g., antibacterial. The regulatory frame applied to pre-clinical and early clinical studies is also outlined by distinguishing between Advanced Therapy Medicinal Products and Medical Devices.

Indexed as

aliphatic polyesthersbiomaterialscollagenglycosaminoglycanspolysaccharidessilk proteinstissue engineering

Identifiers

PMID34575417
PMCPMC8471088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.