Evidence map›Paper›PMID 34572992›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Exploiting Food-Grade Mesoporous Silica to Preserve the Antioxidant Properties of Fresh Olive Mill Wastewaters Phenolic Extracts.

Federica Ianni, Andrea Gagliardi, Agnese Taticchi, Maurizio Servili, Nicola Pinna, Aurélie Schoubben, Roccaldo Sardella, Stefano Bruscoli

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Effects ofAntioxidants (Basel, Switzerland) · 2022
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Federica IanniDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0003-4293-3100
Andrea GagliardiDepartment of Medicine and Surgery, University of Perugia, Via Gambuli 1, 06132 Perugia, Italy.
Agnese TaticchiDepartment of Agricultural Food and Environmental Sciences, University of Perugia, Via S. Costanzo, 06126 Perugia, Italy.
Maurizio ServiliDepartment of Agricultural Food and Environmental Sciences, University of Perugia, Via S. Costanzo, 06126 Perugia, Italy.
Nicola PinnaDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.
Aurélie SchoubbenDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0002-2567-519X
Roccaldo SardellaDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0001-9856-0230
Stefano BruscoliDepartment of Medicine and Surgery, University of Perugia, Via Gambuli 1, 06132 Perugia, Italy.

Funding

PSR Umbria 2014/2020-Submeasure 16.1 2014IT06RDRP012
6 · The paper itself

Abstract

Fresh olive mill wastewaters phenolic extracts are of great interest as preservatives or fortifying ingredients but are characterized by limited stability. The purpose of this study was to use mesoporous silica to enhance their stability and preserve their antioxidant properties. The phenolic extracts were characterized for their composition by HPLC-DAD and included in a mesoporous matrix with or without a lipid coating. The inclusion complexes were characterized in terms of total phenolic content, radical scavenging capacity and in vitro antioxidative activity and cell compatibility. Besides, inclusion complex stability under different storage conditions (22 and 37 °C, 75% relative humidity, 1 month) was evaluated. The inclusion process was nearly quantitative and modified neither the total phenolic content nor the total antioxidant capacity. None of the inclusion complex concentrations assayed on the HT29 cell line showed toxicity. Moreover, HT29 cells treated with the inclusion complex exhibited a significant antioxidant effect, while the lipid coating impaired the antioxidant activity. The complexes without lipid were stable under all the investigated conditions, while the lipid-coated products were less stable under the more drastic conditions. Overall, inclusion complexes in mesoporous silica have suitable characteristics to be used for different applications, including food supplementation.

Indexed as

cytotoxicityHPLC-DAD analysisinclusion complexintestinal-derived epithelial cell linein vitro antioxidant activityoleaceinolive phenolic compoundsSyloid® AL-1total antioxidant capacitytotal phenol content

Identifiers

PMID34572992
PMCPMC8466964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.