Evidence map›Paper›PMID 34480677›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2021

Affinity-Guided Isolation and Identification of Procyanidin B2 from Mangosteen (Garcinia mangostana L.) Rinds and its In Vitro LPS Binding and Neutralization Activities.

Xinchuan Zheng, Yongjun Yang, Yongling Lu, Qian Chen

Abstract read
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In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Hypoglycemic activity ofFrontiers in pharmacology · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xinchuan ZhengChongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, 400714, China. zhengxinchuan@cigit.ac.cn.ORCID http://orcid.org/0000-0003-4099-812X
Yongjun YangClinical Research Centre, The First Affiliated Hospital, Army Medical University, Chongqing, 400038, China.
Yongling LuClinical Research Centre, The First Affiliated Hospital, Army Medical University, Chongqing, 400038, China.
Qian ChenClinical Research Centre, The First Affiliated Hospital, Army Medical University, Chongqing, 400038, China.
Army Medical University · CNChongqing Institute of Green and Intelligent Technology · CN

Funding

National Natural Science Foundation of China 81803394
6 · The paper itself

Abstract

Garcinia mangostana L. (mangosteen) is a tropical fruit that has been used for medicinal purposes in Southeast Asia for centuries. With an interest in its applications to treat infection, we sought to investigate the bioactive constituents of mangosteen and identified the phenolic compound procyanidin B2 from the mangosteen pericarp by examining lipopolysaccharide (LPS) binding capacity. The LPS binding and neutralization activities of procyanidin B2 were determined by a combination of biophysical and in silico techniques. The affinity of procyanidin B2 to LPS was 1.61 × 10

Indexed as

Garcinia mangostanaBiflavonoidsCatechinFruitLipopolysaccharidesPlant ExtractsProanthocyanidinsBiflavonoidsCatechinLipopolysaccharidesPlant ExtractsProanthocyanidinsprocyanidin B2BindingLPSMangosteenNeutralizationProcyanidin B2

Identifiers

PMID34480677
OpenAlexW3196965477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.