Evidence map›Paper›PMID 34458017›Full record

ArticlePeerJ2021

On the use of sequence-quality information in OTU clustering.

Robert Müller, Markus Nebel

Abstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert Müller *Faculty of Technology, Bielefeld University, Bielefeld, Germany.ORCID 0000-0002-0909-3608
Markus Nebel *Faculty of Technology, Bielefeld University, Bielefeld, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh-throughput sequencing has become an essential technology in life science research. Despite continuous improvements in technology, the produced sequences are still not entirely accurate. Consequently, the sequences are usually equipped with error probabilities. The quality information is already employed to find better solutions to a number of bioinformatics problems (

resultsIn this paper, we present quality-aware clustering methods inspired by quality-weighted alignments and model-based denoising, and explore their applicability to OTU clustering. We implemented the quality-aware methods in a revised version of our

conclusionsThe quality-aware methods expand the iterative,

Indexed as

Operational taxonomic unitsSequence clusteringSequence quality information

Identifiers

PMID34458017
PMCPMC8375510

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.