Evidence map›Paper›PMID 34262713›Full record

ArticleFood science & nutrition2021

In vitro antioxidant and antitumor study of zein/SHA nanoparticles loaded with resveratrol.

Qiankun Shi, Xinya Wang, Xudong Tang, Nuo Zhen, Yupeng Wang, Zhijian Luo, Hao Zhang, Jingsheng Liu, Dongfang Zhou, Keke Huang

Abstract read
In one paragraph

Article in Food science & nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  17. Recent advances in nanocarriers for nutrient delivery.Drug delivery and translational research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qiankun ShiCollege of Food Science and Engineering National Engineering Laboratory for Wheat and Corn Deep Processing Jilin Agricultural University Changchun China.
Xinya WangCollege of Food Science and Engineering National Engineering Laboratory for Wheat and Corn Deep Processing Jilin Agricultural University Changchun China.
Xudong TangDepartment of Food Science Rutgers University New Brunswick NJ USA.
Nuo ZhenCollege of Food Science and Engineering National Engineering Laboratory for Wheat and Corn Deep Processing Jilin Agricultural University Changchun China.
Yupeng WangSchool of Pharmaceutical Sciences Southern Medical University Guangzhou China.
Zhijian LuoSchool of Pharmaceutical Sciences Southern Medical University Guangzhou China.
Hao ZhangCollege of Food Science and Engineering National Engineering Laboratory for Wheat and Corn Deep Processing Jilin Agricultural University Changchun China.ORCID https://orcid.org/0000-0002-8582-8493
Jingsheng LiuCollege of Food Science and Engineering National Engineering Laboratory for Wheat and Corn Deep Processing Jilin Agricultural University Changchun China.
Dongfang ZhouSchool of Pharmaceutical Sciences Southern Medical University Guangzhou China.
Keke HuangState Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of Chemistry Jilin University Changchun China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol (RES) loaded Zein-SHA (low-molecular-weight sodium hyaluronate) nanoparticles with average diameter of about 152.13 nm and polydispersity index (PDI) of 0.122, which can be used to encapsulate, protect and deliver resveratrol. By measuring ABTS free radical scavenging ability and iron (III) reducing power, it was determined that encapsulated resveratrol has higher in vitro antioxidant activity than free resveratrol. When tested with murine breast cancer cells 4T1, the encapsulated resveratrol also showed higher antiproliferative activity than free resveratrol, with IC

Indexed as

anticancer activityantioxidant activitynanoparticlesresveratrolSHAzein

Identifiers

PMID34262713
PMCPMC8269682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.