ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021
MRI-Compatible and Conformal Electrocorticography Grids for Translational Research.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- Brain-Adhesive Bioelectronics With Shape-Morphable and Biodegradable Properties for Stable Brain Signal Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Advancing neural interfaces: a framework for the fabrication and characterization of freestanding micro-nanodevices.Microsystems & nanoengineering · 2026Article
- Long-Term Stable Subdural Recordings Enabled by Fibrosis-Resistant Hydrogel-Integrated µECoG Arrays.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- High-resolution prosthetic hearing with a soft auditory brainstem implant in macaques.Nature biomedical engineering · 2025Article
- Origami-inspired soft fluidic actuation for minimally invasive large-area electrocorticography.Nature communications · 2024Article
- Multiplexed Surface Electrode Arrays Based on Metal Oxide Thin-Film Electronics for High-Resolution Cortical Mapping.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- A soft, scalable and adaptable multi-contact cuff electrode for targeted peripheral nerve modulation.Bioelectronic medicine · 2024Article
- Thin-film implants for bioelectronic medicine.MRS bulletin · 2024Review
- The ultra-thin, minimally invasive surface electrode array NeuroWeb for probing neural activity.Nature communications · 2023Article
- A low-profile electromechanical packaging system for soft-to-flexible bioelectronic interfaces.APL bioengineering · 2023Article
- Neuroprosthetics: from sensorimotor to cognitive disorders.Communications biology · 2023Review
- Multimodal Electrocorticogram Active Electrode Array Based on Zinc Oxide-Thin Film Transistors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Brainmask: an ultrasoft and moist micro-electrocorticography electrode for accurate positioning and long-lasting recordings.Microsystems & nanoengineering · 2023Article
- Integration of hydrogels in microfabrication processes for bioelectronic medicine: Progress and outlook.Frontiers in bioengineering and biotechnology · 2023Review
- Fluidic enabled bioelectronic implants: opportunities and challenges.Journal of materials chemistry. B · 2022Review
- Translational Organic Neural Interface Devices at Single Neuron Resolution.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- X-Ray Markers for Thin Film Implants.Advanced healthcare materials · 2022Article
- Highly-integrated, miniaturized, stretchable electronic systems based on stacked multilayer network materials.Science advances · 2022Article
- Biomedical Microtechnologies Beyond Scholarly Impact.Micromachines · 2021Article
- MRI-Compatible and Conformal Electrocorticography Grids for Translational Research.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intraoperative electrocorticography (ECoG) captures neural information from the surface of the cerebral cortex during surgeries such as resections for intractable epilepsy and tumors. Current clinical ECoG grids come in evenly spaced, millimeter-sized electrodes embedded in silicone rubber. Their mechanical rigidity and fixed electrode spatial resolution are common shortcomings reported by the surgical teams. Here, advances in soft neurotechnology are leveraged to manufacture conformable subdural, thin-film ECoG grids, and evaluate their suitability for translational research. Soft grids with 0.2 to 10 mm electrode pitch and diameter are embedded in 150 µm silicone membranes. The soft grids are compatible with surgical handling and can be folded to safely interface hidden cerebral surface such as the Sylvian fold in human cadaveric models. It is found that the thin-film conductor grids do not generate diagnostic-impeding imaging artefacts (<1 mm) nor adverse local heating within a standard 3T clinical magnetic resonance imaging scanner. Next, the ability of the soft grids to record subdural neural activity in minipigs acutely and two weeks postimplantation is validated. Taken together, these results suggest a promising future alternative to current stiff electrodes and may enable the future adoption of soft ECoG grids in translational research and ultimately in clinical settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.