Evidence map›Paper›PMID 33922786›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Plant Feed Additives as Natural Alternatives to the Use of Synthetic Antioxidant Vitamins on Poultry Performances, Health, and Oxidative Status: A Review of the Literature in the Last 20 Years.

Federico Righi, Rosario Pitino, Carmen L Manuelian, Marica Simoni, Afro Quarantelli, Massimo De Marchi, Eleni Tsiplakou

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Dietary Inclusion of Casimiroa (Veterinary medicine international · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Effect of dietary supplementation withFrontiers in veterinary science · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Effects of DietaryAnimals : an open access journal from MDPI · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Federico RighiDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, Italy.
Rosario PitinoDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, Italy.ORCID 0000-0002-6784-8167
Carmen L ManuelianDepartment of Agronomy, Food, Natural Resources, Animals and Environment, University of Padova, Viale dell' Università 16, 35020 Legnaro, Italy.ORCID 0000-0002-0090-0362
Marica SimoniDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, Italy.ORCID 0000-0003-3920-9744
Afro QuarantelliDepartment of Veterinary Science, University of Parma, Via del Taglio 10, 43126 Parma, Italy.
Massimo De MarchiDepartment of Agronomy, Food, Natural Resources, Animals and Environment, University of Padova, Viale dell' Università 16, 35020 Legnaro, Italy.
Eleni TsiplakouLaboratory of Nutritional Physiology and Feeding, Department of Animal Science, School of Animal Biosciences, Agricultural University of Athens, Iera Odos 75, 11855 Athens, Greece.ORCID 0000-0002-2544-8966
University of Parma · ITUniversity of Padua · ITAgricultural University of Athens · GR

Funding

European Union's Horizon 2020 research and innovation programme 774340
6 · The paper itself

Abstract

Plant feed additives (PFA) such as essential oils, extracts, and by-products from plant processing can be included in poultry diets. A total of 39 peer-reviewed articles were selected from the literature published in the last 20 years (2000-2020) comparing PFA antioxidant effects with synthetic antioxidant vitamins (mainly vitamin E) in poultry nutrition. The PFA can be used as an effective nutritional strategy to face poultry's oxidative stress with positive impact also on their productivity and efficiency. They can partially or completely replace antioxidant synthetic vitamins (the latter administered at doses between 150 and 500 mg/kg) in animal diets, sometimes affecting important physiological functions or expressing synergistic effect with the synthetic antioxidants. It is crucial to take into consideration the issues related to the absorption and the metabolism of these additives and their interaction with gut microbiota. However, some form- and dose-dependent negative effects on growth performances are observed.

Indexed as

antioxidantsessential oilsnatural vitaminsplant by-productplant extractpoultrysynthetic vitaminstocopherolstocopherylvitamin Cvitamin E

Identifiers

PMID33922786
PMCPMC8146777
OpenAlexW3157424561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.