Evidence map›Paper›PMID 33902644›Full record

SynthesisJournal of cardiothoracic surgery2021

Risk factors of postoperative delirium after cardiac surgery: a meta-analysis.

Haiyan Chen, Liang Mo, Hongjuan Hu, Yulan Ou, Juan Luo

2 registry-linked trialsAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 138 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05525702 narecruitingnot on this mapstarted 2023, after this paper: background citation

Effects of Multi-model Virtual Reality Intervention Method to Reduce the Prevalence of Delirium in ICU Patients With Mechanical Ventilation

TypeinterventionalSponsorPeking Union Medical College HospitalRan2023 to 2026Enrolled102ConditionsDeliriumArmsVRFS
NCT07249047 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Correlation Between Optic Nerve Sheath Diameter Measured by Ultrasound and Delirium in Cardiac Surgery

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2026 to 2027Enrolled300ConditionsPostoperative DeliriumArmsOptic nerve sheath diameter (ONSD) ultrasound
3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  13. DEX, Delirium and Dilemma.Brazilian journal of cardiovascular surgery · 2023
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  15. The effect of early mobilization of post-cardiac surgery patients on delirium: a pilot study.European journal of physical and rehabilitation medicine · 2026
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78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haiyan ChenEducation and Training Department, The First Affiliated Hospital of University of South China, Hengyang, China.
Liang MoDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of University of South China, Hengyang, China. liangmohnhy@yeah.net.ORCID http://orcid.org/0000-0002-5264-3660
Hongjuan HuNursing Department, The First Affiliated Hospital of University of South China, Hengyang, China. 1213887302@qq.com.
Yulan OuNursing Department, The First Affiliated Hospital of University of South China, Hengyang, China.
Juan LuoDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of University of South China, Hengyang, China.

Funding

the construction and practice of the prevention and treatment mode of stress injury in primary hospitals based on "Internet +" 20200769
6 · The paper itself

Abstract

backgroundPostoperative delirium is a frequent event after cardiac surgery. This meta-analysis aimed to identify relevant risk factors.

methodIn this meta-analysis, all original researches regarding patients undergoing mixed types of cardiac surgery (excluding transcatheter procedures) and postoperative delirium were evaluated for inclusion. On July 28th 2020, we searched PubMed, Embase, Web of Science and Scopus. Data about name of first author, year of publication, inclusion and exclusion criteria, research design, setting, method of delirium assessment, incidence of delirium, odds ratio (OR) and corresponding 95% confidence interval (CI) of risk factors, and other information relevant was collected. OR and 95% CI were used as metrics for summarized results. Random effects model was applied.

resultsFourteen reports were included with a total sample size of 13,286. The incidence of delirium ranged from 4.1 to 54.9%. Eight risk factors were identified including aging, diabetes, preoperative depression, mild cognitive impairment, carotid artery stenosis, NYHA functional class III or IV, time of mechanical ventilation and length of intensive care unit stay.

conclusionIn this study several risk factors associated with postoperative delirium after cardiac surgery were identified. Utilizing the information may allow us to identifying patients at high risk of developing postoperative delirium prior to delirium onset.

Indexed as

Age FactorsCardiac Surgical ProceduresCarotid StenosisCognitive DysfunctionDeliriumDepressionDiabetes MellitusHumansIntensive Care UnitsLength of StayPostoperative ComplicationsRespiration, ArtificialRisk FactorsCardiac surgeryMeta-analysisPostoperative delirium

Identifiers

PMID33902644
PMCPMC8072735

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.