Evidence map›Paper›PMID 33807218›Full record

ArticleFoods (Basel, Switzerland)2021

Hesperidin and Naringin Improve Broiler Meat Fatty Acid Profile and Modulate the Expression of Genes Involved in Fatty Acid β-oxidation and Antioxidant Defense in a Dose Dependent Manner.

Ariadne L Hager-Theodorides, Theofilos Massouras, Panagiotis E Simitzis, Katerina Moschou, Evangelos Zoidis, Eleni Sfakianaki, Katerina Politi, Maria Charismiadou, Michael Goliomytis, Stelios Deligeorgis

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Antioxidants (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Nutrigenomics of Natural Antioxidants in Broilers.Antioxidants (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Hesperidin alleviates zinc-induced nephrotoxicity via the gut-kidney axis in swine.Frontiers in cellular and infection microbiology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ariadne L Hager-TheodoridesLaboratory of Animal Breeding and Husbandry, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.ORCID 0000-0002-8480-3200
Theofilos MassourasLaboratory of Dairy Science and Technology, Department of Food Science and Human Nutrition, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.ORCID 0000-0002-5419-1290
Panagiotis E SimitzisLaboratory of Animal Breeding and Husbandry, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.ORCID 0000-0002-1450-4037
Katerina MoschouLaboratory of Dairy Science and Technology, Department of Food Science and Human Nutrition, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.
Evangelos ZoidisLaboratory of Nutritional Physiology and Feeding, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.ORCID 0000-0002-4141-7772
Eleni SfakianakiLaboratory of Animal Breeding and Husbandry, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.ORCID 0000-0001-7636-0182
Katerina PolitiLaboratory of Animal Breeding and Husbandry, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.ORCID 0000-0002-6399-2735
Maria CharismiadouLaboratory of Animal Breeding and Husbandry, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.
Michael GoliomytisLaboratory of Animal Breeding and Husbandry, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.ORCID 0000-0001-9606-9894
Stelios DeligeorgisLaboratory of Animal Breeding and Husbandry, Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.
Agricultural University of Athens · GR

Funding

Ministry of National Education and Religious Affairs MIS 380231
6 · The paper itself

Abstract

The beneficial properties of the flavanones hesperidin and naringin as feed additives in poultry have lately been under investigation. In broilers, both flavanones have been shown to exhibit antioxidant properties while their individual effects on fatty acid (FA) composition and the underlying molecular mechanisms of their activity have not been explored. Here, we studied their effects on broiler meats' FA profiles and on the expression of genes related to lipid metabolism, antioxidant defense and anti-inflammatory function. The experimental design comprised six treatment groups of broilers, each supplemented from day 11 until slaughter at 42 days with hesperidin, naringin or vitamin E, as follows: the E1 group received 0.75 g of hesperidin per kg of feed, E2 received 1.5 g hesperidin/kg feed, N1 received 0.75 g naringin/kg feed, N2 received 1.5 g naringin/kg feed, vitamin E (VE) received 0.2 g a-tocopheryl acetate/kg feed, and the control group was not provided with a supplemented feed. The VE treatment group served as a positive control for antioxidant activity. An analysis of the FA profiles of the abdominal adipose tissue (fat pad),

Indexed as

antioxidantscitrus flavanonesFA beta-oxidationfatty acidsglutathionehepatic gene expressionlipid metabolism

Identifiers

PMID33807218
PMCPMC8065613
OpenAlexW3145903810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.