Evidence map›Paper›PMID 33719024›Full record

ArticleWorld journal of microbiology & biotechnology2021

Lactic acid production using cheese whey based medium in a stirred tank reactor by a ccpA mutant of Lacticaseibacillus casei.

Mariela Verónica Catone, María Mercedes Palomino, Danilo Mario Legisa, Joaquina Fina Martin, Vicente Monedero García, Sandra Mónica Ruzal, Mariana Claudia Allievi

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Lactic acid production byFrontiers in bioengineering and biotechnology · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mariela Verónica Catone *Centro de Investigación y Desarrollo en Biotecnología Industrial, Instituto Nacional de Tecnología Industrial (INTI), Av. General Paz 5445, B1650AAC, San Martín, Buenos Aires, Argentina.
María Mercedes Palomino *Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires - Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN) - CONICET, Ciudad Universitaria, C1428EGA, CABA, Argentina.
Danilo Mario LegisaCentro de Investigación y Desarrollo en Biotecnología Industrial, Instituto Nacional de Tecnología Industrial (INTI), Av. General Paz 5445, B1650AAC, San Martín, Buenos Aires, Argentina.
Joaquina Fina MartinDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires - Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN) - CONICET, Ciudad Universitaria, C1428EGA, CABA, Argentina.
Vicente Monedero GarcíaInstituto de Agroquímica y Tecnología de Alimentos-Consejo Superior de Investigaciones Científicas (IATA-CSIC), Av. Agustín Escardino 7, 46980, Paterna, Valencia, España.
Sandra Mónica RuzalDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires - Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN) - CONICET, Ciudad Universitaria, C1428EGA, CABA, Argentina.
Mariana Claudia AllieviDepartamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires - Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN) - CONICET, Ciudad Universitaria, C1428EGA, CABA, Argentina. mallievi@qb.fcen.uba.ar.ORCID http://orcid.org/0000-0002-8782-2810
Consejo Nacional de Investigaciones Científicas y Técnicas · ARNational Institute of Industrial Technology · ARConsejo Superior de Investigaciones Científicas · ES

Funding

Secretaria de Ciencia y Tecnica, Universidad de Buenos Aires 20020170100019BASecretaria de Ciencia y Tecnica, Universidad de Buenos Aires 20020170200329BA
6 · The paper itself

Abstract

In lactobacilli, CcpA is known to modulate the expression of genes involved in sugar metabolism, stress response and aerobic adaptation. This study aimed to evaluate a ccpA mutant of Lacticaseibacillus casei BL23 to increase lactic acid production using cheese whey. The ccpA derivative (BL71) showed better growth than the L. casei wild-type in the whey medium. In a stirred tank reactor, at 48 h, lactate production by BL71 was eightfold higher than that by BL23. In batch fermentations, the final values reached were 44.23 g L

Indexed as

CheeseBacterial ProteinsBatch Cell Culture TechniquesBioreactorsCarbohydrate MetabolismCulture MediaDairyingDNA-Binding ProteinsFermentationHydrogen-Ion ConcentrationIndustrial WasteLactic AcidLactobacillaceaeWheyBacterial ProteinsCulture MediaDNA-Binding ProteinsIndustrial WasteLactic AcidCcpACheese wheyLactic acidLacticaseibacillus caseiProteolytic system

Identifiers

PMID33719024
OpenAlexW3135967518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.