Evidence map›Paper›PMID 33689135›Full record

ArticleProbiotics and antimicrobial proteins2021

Evaluation of GABA Production and Probiotic Activities of Enterococcus faecium BS5.

Sabna Bs, Bency Thankappan, Ramasamy Mahendran, Gayathri Muthusamy, Daniel Raja Femil Selta, Jayaraman Angayarkanni

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  4. Isolation and genetic analysis of anBiochemistry and biophysics reports · 2026
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  13. EvaluatingFood science & nutrition · 2024
    Article
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  19. Progress in the application of Enterococcus faecium in animal husbandry.Frontiers in cellular and infection microbiology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sabna BsDepartment of Microbial Biotechnology, Bharathiar University, Coimbatore, T.N., 641 046, India.
Bency ThankappanDepartment of Microbial Biotechnology, Bharathiar University, Coimbatore, T.N., 641 046, India.
Ramasamy MahendranDepartment of Microbial Biotechnology, Bharathiar University, Coimbatore, T.N., 641 046, India.
Gayathri MuthusamyDepartment of Microbial Biotechnology, Bharathiar University, Coimbatore, T.N., 641 046, India.
Daniel Raja Femil SeltaDepartment of Biochemistry, Bharathiar University, Coimbatore, T.N., 641 046, India.
Jayaraman AngayarkanniDepartment of Microbial Biotechnology, Bharathiar University, Coimbatore, T.N., 641 046, India. angaibiotech@buc.edu.in.
Bharathiar University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gamma-aminobutyric acid (GABA) is a principal inhibitory neurotransmitter in the central nervous system and is produced by irreversible decarboxylation of glutamate. It possesses several physiological functions such as neurotransmission, diuretic, and tranquilizer effects and also regulates cardiovascular functions such as blood pressure and heart rate in addition to playing a role in the reduction of pain and anxiety. The objective of this study was to evaluate the GABA producing ability and probiotic capability of certain lactic acid bacteria strains isolated from dairy products. Around sixty-four bacterial isolates were collected and screened for their ability to produce GABA from monosodium glutamate, among which nine isolates were able to produce GABA. The most efficient GABA producer was Enterococcus faecium BS5. Further, assessment of several important and desirable probiotic properties showed that Ent. faecium BS5 was resistant to acid stress, bile salt, and antibiotics. Ent. faecium BS5 may potentially be used for large-scale industrial production of GABA and also for functional fermented product development.

Indexed as

Enterococcus faeciumProbioticsgamma-Aminobutyric Acidgamma-Aminobutyric AcidDairy productsGamma-aminobutyric acidLactic acid bacteriaProbioticsScreening and production

Identifiers

PMID33689135
OpenAlexW3133722399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.