Evidence map›Paper›PMID 33670720›Full record

Trial reportNutrients2021

A Three-Month Consumption of Eggs Enriched with ω-3, ω-5 and ω-7 Polyunsaturated Fatty Acids Significantly Decreases the Waist Circumference of Subjects at Risk of Developing Metabolic Syndrome: A Double-Blind Randomized Controlled Trial.

Monique T Ngo Njembe, Barbara Pachikian, Irina Lobysheva, Nancy Van Overstraeten, Louis Dejonghe, Eleonore Verstraelen, Marine Buchet, Catherine Rasse, Cécile Gardin, Eric Mignolet and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Monique T Ngo NjembeLouvain Institute of Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Barbara PachikianCenter of Investigation in Clinical Nutrition, UCLouvain, 1348 Louvain-la-Neuve, Belgium.ORCID 0000-0002-8170-352X
Irina LobyshevaInstitute of Experimental and Clinical Research, Pole of Pharmacology and Therapeutics, UCLouvain, 1200 Woluwe-Saint-Lambert, Belgium.ORCID 0000-0002-4290-3625
Nancy Van OverstraetenInstitute of Experimental and Clinical Research, Pole of Pharmacology and Therapeutics, UCLouvain, 1200 Woluwe-Saint-Lambert, Belgium.ORCID 0000-0001-5330-6706
Louis DejongheLouvain Institute of Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Eleonore VerstraelenLouvain Institute of Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Marine BuchetLouvain Institute of Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Catherine RasseLouvain Institute of Data Analysis and Modeling in economics and statistics, Statistical Methodology and Computing Service, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Cécile GardinLouvain Institute of Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Eric MignoletLouvain Institute of Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
Jean-Luc BalligandInstitute of Experimental and Clinical Research, Pole of Pharmacology and Therapeutics, UCLouvain, 1200 Woluwe-Saint-Lambert, Belgium.
Yvan LarondelleLouvain Institute of Biomolecular Science and Technology, UCLouvain, 1348 Louvain-la-Neuve, Belgium.
UCLouvain · BE

Funding

Walloon Region of Belgium ; Fondation Louvain Proof of Concept (POC 2018) project
6 · The paper itself

Abstract

Alpha-linolenic acid (ALA), docosahexaenoic acid (DHA), rumenic acid (RmA), and punicic acid (PunA) are claimed to influence several physiological functions including insulin sensitivity, lipid metabolism and inflammatory processes. In this double-blind randomized controlled trial, we investigated the combined effect of ALA, DHA, RmA and PunA on subjects at risk of developing metabolic syndrome. Twenty-four women and men were randomly assigned to two groups. Each day, they consumed two eggs enriched with oleic acid (control group) or enriched with ALA, DHA, RmA, and PunA (test group) for 3 months. The waist circumference decreased significantly (-3.17 cm;

Indexed as

EggsFood, FortifiedAdultAgedalpha-Linolenic AcidCardiometabolic Risk FactorsCholesterol, HDLDietDocosahexaenoic AcidsDouble-Blind MethodFatty Acids, UnsaturatedFemaleHumansLinoleic Acids, ConjugatedLinolenic AcidsLipoproteins, LDL9,11-linoleic acidalpha-Linolenic AcidCholesterol, HDLDocosahexaenoic AcidsFatty Acids, UnsaturatedLinoleic Acids, ConjugatedLinolenic AcidsLipoproteins, LDLpunicic acidAlpha-linolenic aciddocosahexaenoic acidenriched eggsmetabolic syndromeobesitypunicic acidrumenic acidwaist circumference

Identifiers

PMID33670720
PMCPMC7923083
OpenAlexW3130493087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.