ReviewPoultry science2021
Centennial Review: Effects of vitamins A, D, E, and C on the chicken immune system.
Review in Poultry science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 63 citations in OpenAlex.
- Physiological benefits of protected AD3E on nutrient digestibility, hematology, and small intestinal morphology and carcass characteristics in fattening lambs.Veterinary and animal science · 2026Article
- The effect of increasing dietary Vitamin E and D doses on the performance of broilers andVeterinary and animal science · 2026Article
- Mitigating high-density housing stress in broilers: a comparative evaluation of vitamin E vs. Zinc on immunity, molecular markers, carcass yield, and profitability.Tropical animal health and production · 2026Article
- Causal relationship between trace elements and pityriasis rosea: A Mendelian randomization analysis.Medicine · 2026Article
- The impact of tomato pomace silage on feed utilization, health status, milk yield, and composition in dairy cows.Animal bioscience · 2026Article
- Timing of an antioxidant-acidifier feed additive modulates growth performance and cecal microbiota in broiler chickens during enrofloxacin exposure.Poultry science · 2026Article
- Vitamins impacting mental/physical well-being during viral pandemics: a mechanistic review based on COVID-19: a comprehensive review.Inflammopharmacology · 2026Review
- Oral vitamin DPoultry science · 2026Article
- Ultra-processed foods and accelerated aging in adults: an emerging public health challenge for nutrition and functional health.Frontiers in nutrition · 2026Review
- Isolation, antibiogram and whole genome sequence analysis of Pasteurella multocida type A from layer birds.PloS one · 2026Article
- Preliminary Study on the Mechanism of the Influence of Saline Oat Pasture on Muscle Metabolism and Meat Quality of Tibetan Sheep.Foods (Basel, Switzerland) · 2025Article
- Effect of forced molting on the antioxidant status of laying hens and a new strategy for alleviating postmolting syndrome.Open veterinary journal · 2025Article
- Effects of 1,25-Dihydroxycholecalciferol Glycoside Supplementation on the Growth, Intestinal Health, and Immunity of Broilers from Breeders Supplemented or Not with the Same Additive.Veterinary sciences · 2025Article
- Effects of supplementation with vitamin DFrontiers in veterinary science · 2025Article
- The Combined Use of Cinnamaldehyde and Vitamin C Is Beneficial for Better Carcass Character and Intestinal Health of Broilers.International journal of molecular sciences · 2024Article
- Deposition and enrichment of carotenoids in livestock products: An overview.Food chemistry: X · 2024Review
- Effects of Combinations of Dietary Vitamin C and Acetylsalicylic Acid on Growth Performance, Carcass Traits and, Serum and Immune Response Parameters in Broilers.Animals : an open access journal from MDPI · 2024Article
- Effects of Electrolyte Multivitamins and Neomycin on Immunity and Intestinal Barrier Function in Transported Lambs.Animals : an open access journal from MDPI · 2024Article
- The effect of different levels of vitamin C and chromium on growth performance, carcass characteristics, digestive organs, immunity, blood constituents, liver enzymes, cecal microflora, meat sensory taste and fatty acid profile of breast meat in broilers.Veterinary medicine and science · 2023Article
- Effects of supplementing organic- and inorganic-based selenium with vitamin E on intestinal histomorphology, caecal bacterial proliferation, and short-chain fatty acid profile in layer hens.Tropical animal health and production · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamins are nutritional elements which are necessary for essential activities such as development, growth, and metabolism of cells. In addition to these conventional functions, vitamins A, D, E, and C have vital roles in normal function of the immune system as their deficiency is known to impair innate and adaptive host responses. By altering transcription of multiple immune system genes and contributing to antioxidant activities, these vitamins influence the immune system in different ways including modulation of cell-mediated and antibody-mediated responses, immunoregulation, and antiinflammatory effects. Furthermore, supplementation of these vitamins to poultry may assist the immune system to combat microbial pathogens while reducing detrimental effects associated with stress and enhancing responses to vaccines. In this article, the relationship between the chicken immune system and vitamins A, D, E, and C is reviewed, and evidence from the literature pertaining to how these vitamins exert their antiinflammatory, regulatory, and antimicrobial effects is discussed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.