Evidence map›Paper›PMID 33561978›Full record

ArticleMolecules (Basel, Switzerland)2021

Membrane Filtration-Assisted Enzymatic Hydrolysis Affects the Biological Activity of Potato Juice.

Przemysław Łukasz Kowalczewski, Anna Olejnik, Iga Rybicka, Magdalena Zielińska-Dawidziak, Wojciech Białas, Grażyna Lewandowicz

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Przemysław Łukasz KowalczewskiDepartment of Food Technology of Plant Origin, Faculty of Food Science and Nutrition, Poznań University of Life Sciences, 31 Wojska Polskiego St., 60-624 Poznań, Poland.ORCID 0000-0002-0153-4624
Anna OlejnikDepartment of Biotechnology and Food Microbiology, Poznań University of Life Sciences, 48 Wojska Polskiego St., 60-627 Poznań, Poland.ORCID 0000-0002-4385-0051
Iga RybickaDepartment of Technology and Instrumental Analysis, Poznań University of Economics and Business, Al. Niepodległości 10, 61-875 Poznań, Poland.ORCID 0000-0003-1679-328X
Magdalena Zielińska-DawidziakDepartment of Biochemistry and Food Analysis, Faculty of Food Science and Nutrition, 48 Mazowiecka St., Poznań University of Life Sciences, 60-623 Poznań, Poland.ORCID 0000-0003-1535-9625
Wojciech BiałasDepartment of Biotechnology and Food Microbiology, Poznań University of Life Sciences, 48 Wojska Polskiego St., 60-627 Poznań, Poland.ORCID 0000-0002-6095-3167
Grażyna LewandowiczDepartment of Biotechnology and Food Microbiology, Poznań University of Life Sciences, 48 Wojska Polskiego St., 60-627 Poznań, Poland.ORCID 0000-0003-3967-112X
University of Life Sciences in Poznań · PLPoznań University of Economics and Business · PL

Funding

National Science Centre (Poland) 2019/03/X/NZ9/00229
6 · The paper itself

Abstract

The results of recently published studies indicate that potato juice is characterized by interesting biological activity that can be particularly useful in the case of gastrointestinal symptoms. Moreover, the studies also described the high nutritional value of its proteins. This article is a report on the impact of the enzymatic hydrolysis of proteins combined with membrane filtration. The obtained potato juice protein hydrolysate (PJPH) and its concentrate (cPJPH) were characterized in terms of their nutritional value and biological activity. The amino acid profile and scoring, the content of mineral compounds, and the antioxidant and in vitro cytotoxic activity were assessed. The study proved that the antioxidant activity of PJPH is higher than that of fresh potato juice, and the cytotoxicity against human gastric carcinoma cell line (Hs 746T), human colon cancer cell line (Caco-2), human colorectal adenocarcinoma cell line (HT-29), and human normal colon mucosa cell line (CCD 841 CoN) showed biological activity specifically targeted against cancer cells. Therefore, it can be concluded that the membrane filtration-assisted enzymatic hydrolysis of potato juice proteins may increase their biological activity and allow for potato juice to be used in the production of medicinal preparations.

Indexed as

Cell Line, TumorCell MembraneFruit and Vegetable JuicesHumansHydrolysisNutritive ValueSerine EndopeptidasesSolanum tuberosummicrobial serine proteinasesSerine Endopeptidasesantioxidant activityantiproliferative activitycancer cellscytotoxicityin vitro studynutritional value

Identifiers

PMID33561978
PMCPMC7914785
OpenAlexW3127651331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.