Evidence map›Paper›PMID 33321939›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Impact of Enzymatic and Microbial Bioprocessing on Antioxidant Properties of Hemp (

Erica Pontonio, Michela Verni, Cinzia Dingeo, Elixabet Diaz-de-Cerio, Daniela Pinto, Carlo Giuseppe Rizzello

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Optimization Co-Culture ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  7. Article
  8. Hemp Seeds (Molecules (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Hemp Seed Fermented byFoods (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Erica PontonioDepartment of Soil, Plant and Food Science, University of Bari Aldo Moro, Giovanni Amendola 165/A, 70126 Bari, Italy.ORCID 0000-0003-1735-836X
Michela VerniDepartment of Soil, Plant and Food Science, University of Bari Aldo Moro, Giovanni Amendola 165/A, 70126 Bari, Italy.ORCID 0000-0001-6767-5035
Cinzia DingeoDepartment of Soil, Plant and Food Science, University of Bari Aldo Moro, Giovanni Amendola 165/A, 70126 Bari, Italy.
Elixabet Diaz-de-CerioDepartment of Nutrition and Food Science, University of Granada, 18071 Granada, Spain.
Daniela PintoGiuliani S.p.A., Pelagio Palagi, 2, 20129 Milan, Italy.
Carlo Giuseppe RizzelloDepartment of Environmental Biology, "Sapienza" University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-0425-2892
University of Bari Aldo Moro · ITGiuliani (Italy) · ITSapienza University of Rome · ITUniversidad de Granada · ES

Funding

Regione Puglia Can.A.P.A. Canapa per la produzione alimentare BURP n.101 (5.09.2019)
6 · The paper itself

Abstract

Although the hemp seed boasts high nutritional and functional potential, its use in food preparations is still underestimated due to scarce technological properties and the presence of several anti-nutritional factors. Here, an optimization of a biotechnological protocol aimed at improving the antioxidant properties and the protein digestibility of the whole hemp seed has been proposed. Processing based on the use of commercial food grade enzymes and ad hoc selected lactic acid bacteria was tested and the phenolic and protein profiles were investigated through an integrated approach including selective extraction, purification, and identification of the potentially active compounds. The influence of the bioprocessing on the antioxidant activity of the hemp was evaluated both in vitro and on human keratinocytes. The lactic acid bacteria fermentation was the best method to significantly improve the antioxidant potential of the hemp through intense proteolysis which led to both the release of bioactive peptides and the increase in the protein digestibility. Moreover, changes in the phenolic profile allowed a significant protective effect against oxidative stress measured on the human keratinocyte cell line.

Indexed as

antioxidant activitybioprocessinghemplactic acid bacteriaproteolysis

Identifiers

PMID33321939
PMCPMC7763576
OpenAlexW3111910487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.