Evidence map›Paper›PMID 32844160›Full record

ArticleBMC chemistry2020

Carcinogenic and neurotoxic risks of dietary acrylamide consumed through cereals among the Lebanese population.

Areej Merhi, Ghada El-Zakhem Naous, Ralph Daher, Martine Abboud, Mohamad Mroueh, Robin I Taleb

Open access · goldAbstract read
In one paragraph

Article in BMC chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Acrylamide in Corn-Based Thermally Processed Foods: A Review.Journal of agricultural and food chemistry · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Areej MerhiSchool of Arts and Sciences, Department of Natural Sciences, Lebanese American University, Byblos, Beirut, Lebanon.
Ghada El-Zakhem NaousSchool of Arts and Sciences, Department of Natural Sciences, Lebanese American University, Byblos, Beirut, Lebanon.
Ralph DaherSchool of Arts and Sciences, Department of Natural Sciences, Lebanese American University, Byblos, Beirut, Lebanon.
Martine AbboudDepartment of Chemistry, University of Oxford, Oxford, UK.
Mohamad MrouehSchool of Pharmacy, Department of Pharmaceutical Sciences, Lebanese American University, Byblos, Lebanon.
Robin I TalebSchool of Arts and Sciences, Department of Natural Sciences, Lebanese American University, Byblos, Beirut, Lebanon.ORCID 0000-0001-8033-6951
Lebanese American University · LBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aims to determine the carcinogenic and neurotoxic risks associated with acrylamide intake from cereal products. Analysis on a UPLC-MS/MS spectrometer revealed that oat-based and mixed cereals contain the highest amount of acrylamide among cereal products with levels as high as 271 and 348 μg/kg, respectively. Children were shown to exhibit both carcinogenic and neurotoxic risks regardless of the type of cereal product consumed. For adults above 50 years of age, only consumers of oat-based cereal products seem to exhibit carcinogenic and neurotoxic risks. To avoid a carcinogenic and neurotoxic risk among the Lebanese population, we propose that food processors set the maximum tolerable concentration for acrylamide in cereal products at 94.8 μg/kg product, a value which is threefolds lower than the average acrylamide levels found in this study. Alternatively, and unreasonably, the average Lebanese population and children among the Lebanese population may choose to cut down on cereal consumption by 1.7- and 7.2-folds respectively, should they want to avoid a health hazard as a result of acrylamide intake. The industry should also respond by optimizing the production process in a way to reduce acrylamide levels in cereals.

Indexed as

AcrylamideCarcinogenicCerealsLC–MS/MSNeurotoxicWHO

Identifiers

PMID32844160
PMCPMC7439519
OpenAlexW3058910771

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.