ArticleProbiotics and antimicrobial proteins2021
Probiotic Properties of Lactobacilli and Their Ability to Inhibit the Adhesion of Enteropathogenic Bacteria to Caco-2 and HT-29 Cells.
Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.
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Who cites it
90 citing papers in PubMed, 178 citations in OpenAlex.
- L-Glutamic acid production by lactic acid bacteria from Brazilian fermented foods: screening, optimization, and probiotic-related properties of Limosilactobacillus fermentum CCMA 0205.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- In vitro Evaluation of Immunomodulatory and Antioxidant Potential of Isolated Lactic Acid Bacteria from Iranian Dairy Products: An Insight into beneficial potential of cheese-derived isolates.Probiotics and antimicrobial proteins · 2026Article
- Mechanistic Insights into Honey-Mediated Antibacterial Activity Against Enterobacteriaceae: A Multifaceted Approach Targeting Membrane Integrity, Protein Synthesis, and Quorum Sensing Inhibition.Probiotics and antimicrobial proteins · 2026Article
- Comprehensive Evaluation of Safety, Functional Properties, and Immunomodulatory Activity of 19 Probiotic Strains Approved by the Ministry of Food and Drug Safety (MFDS).Journal of microbiology and biotechnology · 2026Article
- Genomic and Phenotypic Characterization of the Probiotic Potential and Safety of Bacillus velezensis CH3-2 Isolated from Chahua Chicken.Probiotics and antimicrobial proteins · 2026Article
- Prospects and challenges in using engineered lactic acid bacteria in aquaculture applications.Engineering microbiology · 2026Review
- Genetically engineered probiotic E. coli Nissle 1917 enhances protection against Salmonella via increased adhesion and systemic T-cell responses.NPJ biofilms and microbiomes · 2026Article
- Probiotic potential and antioxidant, antidiabetic, and anticancer activities of goat milk-derived lactic acid bacteria.Folia microbiologica · 2026Article
- Article
- Improving Gut Microbiota and Growth Performance of Edible Crickets (Microorganisms · 2026Article
- WGS analysis and functional studies illustrate promising gene-signatures for probiotic attributes and molecular-targeted therapeutic prospects of Lactiplantibacillus plantarum LP-ARP2.Archives of microbiology · 2026Article
- Lactiplantibacillus plantarum P16 mitigated murine colitis through modulation of immune response and gut microbiota.AMB Express · 2026Article
- Lactic Acid Bacteria as the Green and Safe Food Preservatives: Their Mechanisms, Applications and Prospects.Foods (Basel, Switzerland) · 2026Review
- Characterization and Validation of the Antibacterial Activity ofFoods (Basel, Switzerland) · 2026Article
- Screening of probiotics for promoting mineral absorption based onFrontiers in microbiology · 2026Article
- Multifunctional antimicrobial effects ofFrontiers in immunology · 2026Article
- Potential Lactic Acid Bacteria Characterized From the Gastrointestinal Tract of Butter Catfish,International journal of microbiology · 2026Article
- In vitro evaluation of Bacillus subtilis isolated from Apis mellifera for potential use as a probiotic feed additive in honeybees.Scientific reports · 2025Article
- Evaluating the Probiotic Profile, Antioxidant Properties, and Safety of Indigenous Lactobacillus spp. Inhabiting Fermented Green Tender Coconut Water.Probiotics and antimicrobial proteins · 2025Article
- Safety Assessment and Probiotic Potential of a Novel SpeciesNutrients · 2025Article
30 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluated the probiotic properties of lactic acid bacteria using resistance, safety, and functional assays. A preliminary subtractive screening of nineteen strains was performed based on their survival in simulated gastric and intestinal juice, and cell surface characteristics (hydrophobicity and auto-aggregation). Five strains were selected for further characterization, which included the assessment of their co-aggregation to pathogens, phenol tolerance, antimicrobial activity, and safety. Moreover, their adhesion to Caco-2 and HT-29 cells and the ability to inhibit pathogenic bacteria adhesion were evaluated. All strains had high (≥ 80.0%) survival rates in gastric and intestinal juices. Among them, Lactobacillus brevis CCMA 1284, L. plantarum CCMA 0743, and L. plantarum CCMA 0359 exhibited higher hydrophobicity (95.33, 96.06, and 80.02%, respectively), while L. paracasei CCMA 0504 and L. paracasei CCMA 0505 had the highest auto-aggregation values (45.36 and 52.66%, respectively). However, these last two strains were positive for the DNAse test, which is a safety concern. The CCMA 0359 and CCMA 1284 strains did not show antimicrobial activity, while the CCMA 0505 strain had a higher percentage of adhesion (4.75%) to Caco-2 cells. In the simulated competition and exclusion assays, the CCMA 0743 strain was able to reduce Salmonella adhesion to both cells (Caco-2 and HT-29), but only the CCMA 0743 and CCMA 0505 strains inhibited Escherichia coli adhesion to HT-29 cells in the competition assay. According to the results of these evaluated attributes, this strain showed to be an excellent candidate for probiotic use.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.