Evidence map›Paper›PMID 32385687›Full record

ArticleEuropean journal of nutrition2021

Enrichment of bread with beta-glucans or resistant starch induces similar glucose, insulin and appetite hormone responses in healthy adults.

Panagiota Binou, Amalia E Yanni, Athena Stergiou, Konstantinos Karavasilis, Panagiotis Konstantopoulos, Despoina Perrea, Nikolaos Tentolouris, Vaios T Karathanos

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Panagiota BinouLaboratory of Chemistry, Biochemistry, Physical Chemistry of Foods, Department of Nutrition and Dietetics, Harokopio University, 70 El. Venizelou Ave, 17671, Athens, Greece.
Amalia E YanniLaboratory of Chemistry, Biochemistry, Physical Chemistry of Foods, Department of Nutrition and Dietetics, Harokopio University, 70 El. Venizelou Ave, 17671, Athens, Greece. ayanni@hua.gr.ORCID http://orcid.org/0000-0001-7984-7025
Athena StergiouLaboratory of Chemistry, Biochemistry, Physical Chemistry of Foods, Department of Nutrition and Dietetics, Harokopio University, 70 El. Venizelou Ave, 17671, Athens, Greece.
Konstantinos KaravasilisELBISCO S.A., Industrial and Commercial Food Company, 21st Km Marathonos Ave, Pikermi, Attica, Greece.
Panagiotis KonstantopoulosLaboratory of Experimental Surgery and Surgery Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Despoina PerreaLaboratory of Experimental Surgery and Surgery Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nikolaos Tentolouris1st Department of Propaedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Vaios T KarathanosLaboratory of Chemistry, Biochemistry, Physical Chemistry of Foods, Department of Nutrition and Dietetics, Harokopio University, 70 El. Venizelou Ave, 17671, Athens, Greece.
National and Kapodistrian University of Athens · GRHarokopio University of Athens · GR

Funding

ELBISCO S.A. Greece K439
6 · The paper itself

Abstract

purposeβ-Glucans (βG) and resistant starch (RS) are known for their effects on the improvement of glucose tolerance and enhancement of insulin sensitivity. Enrichment of bread with βG or RS was performed to examine potential postprandial benefits regarding gastrointestinal hormone responses.

methodsTen healthy normoglycaemic adults participated in the study and were provided with either a glucose solution (reference food, GS) or bread enriched with β-glucans (βGB) (3.6 g/30 g available CHO) or bread enriched with resistant starch (RSB) (15% of total starch), with 1-week intervals in amounts that yielded 50 g of available carbohydrates. Venous blood samples were collected before consumption and at 15, 30, 45, 60, 90, 120 and 180 min postprandially. Glucose, insulin, ghrelin, glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) responses as well as glycaemic index (GI) and subjective appetite ratings were evaluated.

resultsIngestion of βGB and RSB elicited lower incremental area under the curve (iAUC) for glycaemic response compared to GS (P < 0.05). Both breads demonstrated a low GI (βGB: 48, RSB: 40). There were no significant differences in insulin response, ghrelin, GLP-1 or PYY between the two breads. A significantly lower desire to eat and higher fullness were detected 15 min after βGB and RSB consumption and until 180 min (P < 0.05 compared to GS).

conclusionEnrichment of bread with either βG or RS produced a low GI product but the two breads were not significantly different in relation to insulin, ghrelin, GLP-1 and PYY responses. The development of bread products which cause improved metabolic effects is of great importance for the promotion of public health.

Indexed as

beta-GlucansBreadAdultAppetiteBlood GlucoseCross-Over StudiesDietary FiberGlucoseHumansInsulinPostprandial PeriodResistant StarchStarchbeta-GlucansBlood GlucoseDietary FiberGlucoseInsulinResistant StarchStarchAppetiteBreadGlycaemic indexPostprandial hormone responsesResistant starchβ-glucans

Identifiers

PMID32385687
OpenAlexW3022630987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.