ArticleEvidence-based complementary and alternative medicine : eCAM2020
Phenolics and Carbohydrates in Buckwheat Honey Regulate the Human Intestinal Microbiota.
Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04974450 (Effect of Trigona Honey to Intestinal Microbiota, Lipid Profile and Anthropometric Status in Obese Individuals), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Trigona Honey to Intestinal Microbiota, Lipid Profile and Anthropometric Status in Obese Individuals
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Systematic Review of Human and Animal Evidence on the Role of Buckwheat Consumption on Gastrointestinal Health.Nutrients · 2022Pooled it
- The Intestinal Fate of Phenolic Substances in Honey: Metabolism by Gut Microbiota, Regulation of Bioavailability, and Its Prebiotic Effects on Host Health.Foods (Basel, Switzerland) · 2026Review
- Honey as a Natural Flavorful Product: A Comprehensive Review of Its Potential Biological Activities and Recent Studies.Food science & nutrition · 2026Review
- Mapping Royal Jelly's Bioactive Profile by Liquid Chromatography Coupled to Trapped Ion Mobility Spectrometry and High-Resolution Mass Spectrometry.Journal of agricultural and food chemistry · 2025Article
- Development of an LC-MS/MS Method for Quantitation of Western Honeybee (Journal of applied glycoscience · 2025Article
- Article
- Unraveling the Physicochemical, Nutritional and Antioxidant Properties of the Honey Produced from theFoods (Basel, Switzerland) · 2024Article
- Biotics and bacterial function: impact on gut and host health.The ISME journal · 2024Review
- Integrated HS-GC-IMS and UPLC-Q-Orbitrap HRMS-based metabolomics revealed the characteristics and differential volatile and nonvolatile metabolites of different citrus peels.Current research in food science · 2024Article
- Article
- Evaluation of the antioxidant potency of Greek honey from the Taygetos and Pindos mountains using a combination of cellular and molecular methods.Molecular medicine reports · 2023Article
- Analysis of 18 Free Amino Acids in Honeybee and Bumblebee Honey from Eastern and Northern Europe and Central Asia Using HPLC-ESI-TQ-MS/MS Approach Bypassing Derivatization Step.Foods (Basel, Switzerland) · 2022Article
- Neuroprotective Natural Products' Regulatory Effects on Depression via Gut-Brain Axis Targeting Tryptophan.Nutrients · 2022Review
- Food Additives Associated with Gut Microbiota Alterations in Inflammatory Bowel Disease: Friends or Enemies?Nutrients · 2022Review
- A Sweeter Pill to Swallow: A Review of Honey Bees and Honey as a Source of Probiotic and Prebiotic Products.Foods (Basel, Switzerland) · 2022Review
- Combined Inhibitory Effect of Fir (Antibiotics (Basel, Switzerland) · 2022Article
- The Potential of Honey as a Prebiotic Food to Re-engineer the Gut Microbiome Toward a Healthy State.Frontiers in nutrition · 2022Review
- Phenolic Compounds in Honey and Their Relationship with Antioxidant Activity, Botanical Origin, and Color.Antioxidants (Basel, Switzerland) · 2021Review
- In vitro study of the effect of quinoa and quinoa polysaccharides on human gut microbiota.Food science & nutrition · 2021Article
- Role of gut microbiota-derived metabolites on vascular calcification in CKD.Journal of cellular and molecular medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intestinal microbiota plays an important role in human health. The aim of this paper is to determine the impact of the phenolics and carbohydrate in buckwheat honey on human intestinal microbiota. We investigated the phenolics and carbohydrate compositions of eight buckwheat honey samples using high-performance liquid chromatography and ion chromatography. The human intestinal microbes were cultured in a medium supplemented with eight buckwheat honey samples or the same concentration of fructooligosaccharides. The bacterial 16S rDNA V4 region sequence of DNA extraction was determined by the Illumina MiSeq platform. 12 phenolics and 4 oligosaccharides were identified in almost all buckwheat honey samples, namely, protocatechuic acid, 4-hydroxy benzoic acid, vanillin, gallic acid,
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.