Evidence map›Paper›PMID 31996813›Full record

Trial reportHypertension research : official journal of the Japanese Society of Hypertension2020

Validation of preferred salt concentration in soup based on a randomized blinded experiment in multiple regions in Japan-influence of umami (L-glutamate) on saltiness and palatability of low-salt solutions.

Hitomi Hayabuchi, Rieko Morita, Masanori Ohta, Akiko Nanri, Hideki Matsumoto, Shoji Fujitani, Shintaro Yoshida, Sadayoshi Ito, Atsushi Sakima, Hiroyuki Takase and 2 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Hypertension research : official journal of the Japanese Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

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  11. Cytotechnology · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Hitomi HayabuchiDepartment of Food Science and Nutrition, Faculty of Human Life and Environment, Nara Women's University, Nara, Japan. s-hayabuchi@fwu.ac.jp.
Rieko MoritaGraduate School of Health and Environmental Sciences, Fukuoka Women's University, Fukuoka, Japan.
Masanori OhtaGraduate School of Health and Environmental Sciences, Fukuoka Women's University, Fukuoka, Japan.
Akiko NanriGraduate School of Health and Environmental Sciences, Fukuoka Women's University, Fukuoka, Japan.
Hideki MatsumotoResearch Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc, Kawasaki, Japan.
Shoji FujitaniResearch Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc, Kawasaki, Japan.
Shintaro YoshidaResearch Institute for Bioscience Products & Fine Chemicals, Ajinomoto Co., Inc, Kawasaki, Japan.
Sadayoshi ItoDivision of Nephrology, Endocrinology and Hypertension, Tohoku University Graduate Medicine, Sendai, Japan.
Atsushi SakimaHealth Administration Center, University of the Ryukyus, Okinawa, Japan.
Hiroyuki TakaseEnshu Hospital, Hamamatsu, Japan.
Miho KusakaKusaka Clinic, Kure, Japan.
Takuya TsuchihashiSteel Memorial Yawata Hospital, Kitakyushu, Japan.
Ajinomoto (Japan) · JPFukuoka Women's University · JPJA Shizuoka Koseiren ENSHU hospital · JPNara Women's University · JPNippon Steel Yawata Memorial Hospital · JPTohoku University · JPUniversity of the Ryukyus · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium reduction is an important public health goal. Individual and population approaches are necessary for reducing the sodium content of processed foods and meals. The aim of the present study is to affirm the effect of monosodium L-glutamate (MSG), an umami substance, on the saltiness or palatability of low-salt solutions and to explore the preferred salt concentration in soup. Five hundred and eighty-four healthy participants from nineteen regions in Japan tasted 0.3, 0.6, and 0.9% NaCl solutions with or without 0.3% MSG. Evaluations of saltiness and palatability for each solution were conducted using a visual analog scale in a double-blinded randomized manner. Saltiness gradually increased depending on the concentration of NaCl. The saltiness of the 0.3% NaCl solution with MSG was rated significantly higher than that without MSG. The palatability ratings were higher for the solutions with MSG than for those without MSG for all NaCl concentrations. In particular, the palatability rating of the 0.3% NaCl solution with MSG was twice as high as that without MSG and was significantly higher than that of the other five test solutions. Furthermore, these results were observed to be approximately the same, irrespective of sex, age, region, etc. Salt reduction is believed to result in a loss of palatability. However, our results suggest that umami can compensate for the loss of palatability caused by salt reduction and that the addition of an appropriate amount of an umami substance can facilitate salt reduction from 0.9 to 0.3% without sacrificing palatability.

Indexed as

AdultAgedAged, 80 and overFemaleFood PreferencesHumansJapanMaleMiddle AgedSodium, DietarySodium GlutamateTasteYoung AdultSodium, DietarySodium GlutamateGlutamatePalatabilityRandomized blind experimentSodium reductionUmami

Identifiers

PMID31996813
PMCPMC8075858
OpenAlexW3003613455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.