Evidence map›Paper›PMID 31835748›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Flavanol Polymerization Is a Superior Predictor of α-Glucosidase Inhibitory Activity Compared to Flavanol or Total Polyphenol Concentrations in Cocoas Prepared by Variations in Controlled Fermentation and Roasting of the Same Raw Cocoa Beans.

Kathryn C Racine, Brian D Wiersema, Laura E Griffin, Lauren A Essenmacher, Andrew H Lee, Helene Hopfer, Joshua D Lambert, Amanda C Stewart, Andrew P Neilson

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Antioxidants in Cocoa.Antioxidants (Basel, Switzerland) · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kathryn C RacineDepartment of Food Science and Technology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA.
Brian D WiersemaDepartment of Food Science and Technology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA.
Laura E GriffinPlants for Human Health Institute, Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Kannapolis, NC 28081, USA.
Lauren A EssenmacherDepartment of Food Science and Technology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA.
Andrew H LeeDepartment of Food Science and Technology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA.
Helene HopferDepartment of Food Science, Pennsylvania State University, University Park, PA 16801, USA.ORCID 0000-0001-6925-0241
Joshua D LambertDepartment of Food Science, Pennsylvania State University, University Park, PA 16801, USA.ORCID 0000-0002-2225-7398
Amanda C StewartDepartment of Food Science and Technology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24060, USA.ORCID 0000-0002-1145-330X
Andrew P NeilsonPlants for Human Health Institute, Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Kannapolis, NC 28081, USA.ORCID 0000-0001-5497-663X
Virginia Tech · USNorth Carolina State University · USPennsylvania State University · US

Funding

USDA AFRI 2017-67017-26783
6 · The paper itself

Abstract

Raw cocoa beans were processed to produce cocoa powders with different combinations of fermentation (unfermented, cool, or hot) and roasting (not roasted, cool, or hot). Cocoa powder extracts were characterized and assessed for α-glucosidase inhibitory activity in vitro. Cocoa processing (fermentation/roasting) contributed to significant losses of native flavanols. All of the treatments dose-dependently inhibited α-glucosidase activity, with cool fermented/cool roasted powder exhibiting the greatest potency (IC

Indexed as

flavan-3-olMaillard reactionmelanoidinprocyanidinα-glucosidase

Identifiers

PMID31835748
PMCPMC6943598
OpenAlexW2995453464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.