Evidence map›Paper›PMID 31775353›Full record

Trial reportMolecules (Basel, Switzerland)2019

Effects of Blackcurrant Anthocyanin on Endothelial Function and Peripheral Temperature in Young Smokers.

Toshiko Tomisawa, Naoki Nanashima, Maiko Kitajima, Kasumi Mikami, Shizuka Takamagi, Hayato Maeda, Kayo Horie, Fu-Chih Lai, Tomohiro Osanai

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Potential Vasculoprotective Effects of Blackcurrant (Molecules (Basel, Switzerland) · 2021
    Article
  10. Review
  11. Review
  12. Blackcurrant (Nutrients · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Toshiko TomisawaDepartment of Nursing Sciences, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.ORCID 0000-0002-3428-6719
Naoki NanashimaDepartment of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki-shi, Aomori-ken 036-8564, Japan.ORCID 0000-0002-4729-3432
Maiko KitajimaDepartment of Nursing Sciences, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.
Kasumi MikamiDepartment of Nursing Sciences, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.
Shizuka TakamagiDepartment of Nursing Sciences, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.
Hayato MaedaDepartment of Agriculture and Life Science, Hirosaki University, 3 Bunkyo-cho, Hirosaki, Aomori 036-8561, Japan.ORCID 0000-0002-8546-6250
Kayo HorieDepartment of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki-shi, Aomori-ken 036-8564, Japan.
Fu-Chih LaiCollege of Nursing, Taipei Medical University, 4 No. 250 Wuxing Street, Taipei 11031, Taiwan.
Tomohiro OsanaiDepartment of Nursing Sciences, Hirosaki University Graduate School of Health Sciences, 66-1 Hon-cho, Hirosaki, Aomori 036-8564, Japan.
Hirosaki University · JPTaipei Medical University · TW

Funding

Japan Society for the Promotion of Science 16K00844
6 · The paper itself

Abstract

backgroundBlackcurrant anthocyanin (BCA) is expected to repair endothelial dysfunction, but it remains unclear whether beneficial effects are present in young healthy persons. This study examines whether supplements containing blackcurrant anthocyanin improve endothelial function and peripheral temperature in young smokers.

methodsYoung, healthy male nonsmokers (N group:

resultsUnder no supplement, FMD was unchanged during the 2 h period after smoking in the N group, whereas it was decreased during the 2 h period after smoking in the S group. Under the A supplement, FMD was decreased 1 h after smoking and returned to the baseline level 2 h after smoking in the S group. The skin temperature in the area of the foot dorsum was decreased in the S group after smoking compared with that in the N group, who did not smoke, whereas under A and B supplements, it was higher in the S group compared with that in the N group.

conclusionsBCA could attenuate the smoking-induced acute endothelial dysfunction and improve peripheral temperature in young smokers.

Indexed as

AdultAnthocyaninsDouble-Blind MethodEndothelial CellsEndothelium, VascularHumansMaleOxidative StressRibesSmokersSmokingTemperatureVasodilationYoung AdultAnthocyaninsanthocyaninblackcurrantendothelial functionperipheral temperaturesmoking

Identifiers

PMID31775353
PMCPMC6930610
OpenAlexW2989860916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.