Evidence map›Paper›PMID 31660038›Full record

SynthesisWorld journal of gastroenterology2019

Allicin as add-on therapy for

Xiao-Bei Si, Xu-Min Zhang, Shuai Wang, Yu Lan, Shuo Zhang, Lin-Yu Huo

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Revisiting Therapeutic Strategies forMolecules (Basel, Switzerland) · 2021
    Review
  9. Beneficial Effects of Organosulfur Compounds fromFoods (Basel, Switzerland) · 2021
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Xiao-Bei SiDepartment of Gastroenterology, Beijing Jishuitan Hospital, Beijing 100035, China.
Xu-Min ZhangDepartment of Gastroenterology, Beijing Jishuitan Hospital, Beijing 100035, China.
Shuai WangDepartment of Gastroenterology, Beijing Jishuitan Hospital, Beijing 100035, China.
Yu LanDepartment of Gastroenterology, Beijing Jishuitan Hospital, Beijing 100035, China. lanyu@jsthospital.org.
Shuo ZhangDepartment of Cardiology, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing 100037, China.
Lin-Yu HuoDepartment of Neurology, Beijing Haidian Hospital, Beijing 100080, China.
Beijing Haidian Hospital · CNBeijing Jishuitan Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAllicin (2-propene-1-sulfinothioic acid S-2-propenyl ester, diallyl thiosulfinate) extracted from garlic, has proven activity against

aimTo perform a systemic review of allicin as an add-on treatment for

methodsElectronic databases including MEDLINE, EMBASE, the Web of Science, the Cochrane Database, the China National Knowledge Infrastructure Database, Chinese VIP Information Databases, Chinese Medical Databases, and the Wan-Fang Database were searched for keywords including "allicin", "

resultsA total of eight RCTs consisting of 867 participants (435 from the allicin group and 432 from the control group) were included. Eradication rate in the allicin group (93.33%, 406/435) was significantly higher than that of the control group (83.56%, 361/432) [

conclusionAllicin as an add-on therapy improves

Indexed as

AntacidsAnti-Bacterial AgentsAnti-Infective AgentsClinical Trials as TopicDisulfidesDrug Therapy, CombinationGastric MucosaHelicobacter InfectionsHelicobacter pyloriHumansProton Pump InhibitorsRemission InductionStomach UlcerSulfinic AcidsTreatment OutcomeallicinAntacidsAnti-Bacterial AgentsAnti-Infective AgentsDisulfidesProton Pump InhibitorsSulfinic AcidsAdd-on therapyAllicinHelicobacter pyloriMeta-analysisRandomized controlled trialsSystematic review

Identifiers

PMID31660038
PMCPMC6815797
OpenAlexW2981097129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.