ArticleFood technology and biotechnology2019
Nitric Oxide Synthesis Inhibition and Anti-Inflammatory Effect of Polypeptide Isolated from Chicken Feather Meal in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages.
Article in Food technology and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Sustainable Valorization ofMolecules (Basel, Switzerland) · 2026Article
- Microbial-enzymatic co-fermentation of feather meal for bioactive peptide production and its multi-pathway synergistic regulation of intestinal health in broilers.Poultry science · 2026Article
- Computer-Aided Design ofACS medicinal chemistry letters · 2026Article
- Antioxidant potential and genomic adaptation ofFrontiers in microbiology · 2026Article
- Design and synthesis of enantiopure NHC-silver(i) and NHC-gold(i) complexes with anticancer, anti-inflammatory and antioxidant properties.RSC medicinal chemistry · 2025Article
- Evaluation of the Biological Properties and Antibacterial Activities of the Natural Food Supplement "Epavin" for Liver Detoxification and Protection.Foods (Basel, Switzerland) · 2025Article
- Effects of Different Rearing Methods on the Intestinal Morphology, Intestinal Metabolites, and Gut Microbiota of Lueyang Black-Bone Chickens.Animals : an open access journal from MDPI · 2025Article
- Anti-Inflammatory Effects and Human Skin Safety of the Eastern Traditional HerbLife (Basel, Switzerland) · 2025Article
- Special Issue: "Enzymes and Enzyme Inhibitors-Applications in Medicine and Diagnosis 2.0".International journal of molecular sciences · 2024Article
- Immunomodulatory, Anticancer, and Antioxidative Activities of Bioactive Peptide Fractions from Enzymatically Hydrolyzed White Jellyfish (Foods (Basel, Switzerland) · 2024Article
- The Inhibition Activity of Natural Methoxyflavonoid fromInternational journal of molecular sciences · 2024Article
- Silver and Gold Complexes with NHC-Ligands Derived from Caffeine: Catalytic and Pharmacological Activity.International journal of molecular sciences · 2024Article
- Investigating the cellular antioxidant and anti-inflammatory effects of the novel peptides in lingzhi mushrooms.Heliyon · 2022Article
- Immunomodulatory Activities ofMolecules (Basel, Switzerland) · 2021Article
- Antioxidant and anti-inflammatory peptide fraction from oyster soft tissue by enzymatic hydrolysis.Food science & nutrition · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitric oxide (NO) plays a key role in the pathogenesis of inflammation and has been implicated in endotoxin-induced tissue injury. Chicken feather meal is a rich source of amino acids that may serve as a peptide hydrolysate to inhibit NO activity. Anti-inflammatory hydrolysates of chicken feather meal were prepared and fractionated into five samples based on molecular mass. The smallest fraction (<0.65 kDa) exhibited the highest NO inhibitory activity without cytotoxicity towards macrophage RAW 264.7 cells. Further subfractions were sufficient to obtain amino acid sequences by Q-TOF LC-MS/MS ESI analysis. Of these, the SNPSVAGVR (885.97 Da) peptide and its corresponding pure synthetic peptide have inhibitory activity against NO production by RAW 264.7 cells (IC
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.