Evidence map›Paper›PMID 31528836›Full record

ArticleCurrent developments in nutrition2019

Almond Snacking for 8 wk Increases Alpha-Diversity of the Gastrointestinal Microbiome and Decreases

Jaapna Dhillon, Zhaoping Li, Rudy M Ortiz

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03084003 (Effects of Almond Consumption on Cardiovascular, Metabolomic, and Microbiome Profiles in Millennials), which is not on this map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03084003 nacompletednot on this map

Effects of Almond Consumption on Cardiovascular, Metabolomic, and Microbiome Profiles in Millennials: Implications of Systemic Glucoregulatory Mechanisms

TypeinterventionalSponsorUniversity of California, MercedRan2016 to 2019Enrolled74ConditionsDiet InterventionArmsAlmonds, Graham crackers
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.

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  9. Effects of Low-Energy Diets Supplemented withAnimals : an open access journal from MDPI · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jaapna DhillonSchool of Natural Sciences, University of California, Merced, CA, USA.
Zhaoping LiCenter for Human Nutrition, David Geffen School of Medicine, Department of Medicine, University of California Los Angeles, California, CA USA.
Rudy M OrtizSchool of Natural Sciences, University of California, Merced, CA, USA.
University of California, Merced · USUniversity of California, Los Angeles · US

Funding

Effects of Functional Food Diets on Cardiometabolic and Metabolomics Profiles in Minority YouthK99MD012815 · NIMHD · UNIVERSITY OF CALIFORNIA, MERCED · PI DHILLON, JAAPNA · 2018 to 2019
$211k
NIMHD NIH HHS K99 MD012815
6 · The paper itself

Abstract

backgroundChanges in gut microbiota are associated with cardiometabolic disorders and are influenced by diet. Almonds are a rich source of fiber, unsaturated fats, and polyphenols, all nutrients that can favorably alter the gut microbiome.

objectivesThe aim of this study was to examine the effects of 8 wk of almond snacking on the gut (fecal) microbiome diversity and abundance compared with an isocaloric snack of graham crackers in college freshmen.

methodsA randomized, controlled, parallel-arm, 8-wk intervention in 73 college freshmen (age: 18-19 y; 41 women and 32 men; BMI: 18-41 kg/m

resultsAlmond snacking resulted in 3% greater quantitative alpha-diversity (Shannon index) and 8% greater qualitative alpha-diversity (Chao1 index) than the cracker group after the intervention (

conclusionsAlmond snacking for 8 wk improved alpha-diversity compared with cracker snacking. Incorporating a morning snack in the dietary regimen of predominantly breakfast-skipping college freshmen improved the diversity and composition of the gut microbiome. This trial was registered at clinicaltrials.gov as NCT03084003.

Indexed as

adolescenceamplicon sequence variantsANCOMcardiovascularfunctional foodsgutmetabolismminoritynutrientsnuts

Identifiers

PMID31528836
PMCPMC6736066
OpenAlexW2955266153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.