Evidence map›Paper›PMID 31438562›Full record

ReviewNutrients2019

The Nutraceutical Value of Olive Oil and Its Bioactive Constituents on the Cardiovascular System. Focusing on Main Strategies to Slow Down Its Quality Decay during Production and Storage.

Lorenzo Flori, Sandra Donnini, Vincenzo Calderone, Angela Zinnai, Isabella Taglieri, Francesca Venturi, Lara Testai

Abstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. The Potential of Black Soldier Fly (Foods (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Review
  4. Effect of the Addition of Yellow Mealworm (Foods (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Bioactive Compounds for Customized Brain Health: What Are We and Where Should We Be Heading?International journal of environmental research and public health · 2023
    Review
  7. The Ancient Olive Trees (Plants (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lorenzo FloriDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy.
Sandra DonniniDepartment of Life Sciences, University of Siena, Via A. Moro 2, 53100 Siena, Italy.
Vincenzo CalderoneDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy.
Angela ZinnaiInterdepartmental Research Centre, Nutraceuticals and Food for Health, University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy.
Isabella TaglieriDepartment of Agriculture, Food and Environment, University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy. isabella.taglieri@for.unipi.it.
Francesca VenturiInterdepartmental Research Centre, Nutraceuticals and Food for Health, University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy. francesca.venturi@unipi.it.
Lara TestaiDepartment of Pharmacy, University of Pisa, via Bonanno 6, 56126 Pisa, Italy. lara.testai@unipi.it.

Funding

Progetti Regione Toscana "Progetti di ricerca e sviluppo" FESR 2014-2020 Grant 1- CUP D56G18000160009
6 · The paper itself

Abstract

Cardiovascular diseases represent the principal cause of morbidity and mortality worldwide. It is well-known that oxidative stress and inflammatory processes are strongly implicated in their pathogenesis; therefore, anti-oxidant and anti-inflammatory agents can represent effective tools. In recent years a large number of scientific reports have pointed out the nutraceutical and nutritional value of extra virgin olive oils (EVOO), strongholds of the Mediterranean diet, endowed with a high nutritional quality and defined as functional foods. In regard to EVOO, it is a food composed of a major saponifiable fraction, represented by oleic acid, and a minor unsaponifiable fraction, including a high number of vitamins, polyphenols, and squalene. Several reports suggest that the beneficial effects of EVOO are linked to the minor components, but recently, further studies have shed light on the health effects of the fatty fraction and the other constituents of the unsaponifiable fraction. In the first part of this review, an analysis of the clinical and preclinical evidence of the cardiovascular beneficial effects of each constituent is carried out. The second part of this review is dedicated to the main operating conditions during production and/or storage that can directly influence the shelf life of olive oil in terms of both nutraceutical properties and sensory quality.

Indexed as

Cardiovascular SystemDietary SupplementsHumansOlive OilOlive Oillight exposurenutraceutical valueoleic acidolive oilpackagingpolyphenolsshelf lifestorage temperaturevitamin E

Identifiers

PMID31438562
PMCPMC6770508

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.