Evidence map›Paper›PMID 31367368›Full record

ArticleFood science & nutrition2019

Analysis of antioxidant effect of two tripeptides isolated from fermented grains (Jiupei) and the antioxidative interaction with 4-methylguaiacol, 4-ethylguaiacol, and vanillin.

Yunsong Jiang, Dongrui Zhao, Jinyuan Sun, Xuelian Luo, Hehe Li, Xiaotao Sun, Fuping Zheng

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 61 citations in OpenAlex.

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  18. Advances on Food-Derived Peptidic Antioxidants-A Review.Antioxidants (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yunsong JiangBeijing Advanced Innovation Center for Food Nutrition and Human Health Beijing Technology & Business University (BTBU) Beijing China.
Dongrui ZhaoBeijing Advanced Innovation Center for Food Nutrition and Human Health Beijing Technology & Business University (BTBU) Beijing China.
Jinyuan SunBeijing Advanced Innovation Center for Food Nutrition and Human Health Beijing Technology & Business University (BTBU) Beijing China.ORCID https://orcid.org/0000-0001-6717-9787
Xuelian LuoState Key Laboratory of Infectious Disease Prevention and Control, National Insititue for Communicable Disease Control and Prevention, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Disease Chinese Centre for Disease Control and Prevention Beijing China.
Hehe LiBeijing Advanced Innovation Center for Food Nutrition and Human Health Beijing Technology & Business University (BTBU) Beijing China.
Xiaotao SunBeijing Advanced Innovation Center for Food Nutrition and Human Health Beijing Technology & Business University (BTBU) Beijing China.
Fuping ZhengBeijing Advanced Innovation Center for Food Nutrition and Human Health Beijing Technology & Business University (BTBU) Beijing China.
Beijing Technology and Business University · CNNational Institute for Communicable Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jiupei (fermented grains) is the raw material for Baijiu distillation. The antioxidant activities of peptides Val-Asn-Pro (VNP) and Tyr-Gly-Asp (YGD) identified from Jiupei were evaluated according to in vitro chemical assays (e.g., 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt, 1,1-diphenyl-2-picrylhydrazyl, and oxygen radical absorbance capacity) and 2,2'-azobis (2-methylpropionamide)-dihydrochloride-activated HepG2 cell model. The interaction on antioxidant activities between peptides (VNP and YGD) and three functional phenols (4-methylguaiacol, 4-ethylguaiacol, and vanillin) which were found in Baijiu was also measured. On the basis of the results, two peptides exhibited strong antioxidant ability in oxygen radical absorbance capacity (ORAC) assay. Furthermore, they suppressed the generation of reactive oxygen species. The intracellular antioxidant enzymatic system and nonenzymatic system were also regulated by VNP and YGD. In addition, it was confirmed that partial auxo-action between peptides and phenols appeared mostly in chemical assays. The findings above might indicate that VNP and YGD are potent natural antioxidants in Jiupei even in Baijiu through distillation process and lay the foundation for illustrating the interactions among different functional substances in Baijiu.

Indexed as

antioxidant tripeptidesHepG2 cellsinteraction effectJiupeiphenols

Identifiers

PMID31367368
PMCPMC6657717
OpenAlexW2951777006

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.