Evidence map›Paper›PMID 31137537›Full record

ArticleNutrients2019

The Lipid and Glyceride Profiles of Infant Formula Differ by Manufacturer, Region and Date Sold.

Samuel Furse, Albert Koulman

Open access · goldAbstract readComparative Study
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The biosynthesis of phospholipids is linked to the cell cycle in a model eukaryote.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Observational
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Samuel FurseCore Metabolomics and Lipidomics Laboratory, Wellcome Trust-MRL Institute of Metabolic Science, University of Cambridge, Level 4 Addenbrooke's Treatment Centre, Keith Day Road, Cambridge CB2 0QQ, UK. sf615@cam.ac.uk.ORCID 0000-0003-4267-2051
Albert KoulmanCore Metabolomics and Lipidomics Laboratory, Wellcome Trust-MRL Institute of Metabolic Science, University of Cambridge, Level 4 Addenbrooke's Treatment Centre, Keith Day Road, Cambridge CB2 0QQ, UK. samuel@samuelfurse.com.ORCID 0000-0001-9998-051X
University of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M027252/1NIHR Clinical Research Network Thames Valley and South Midlands Biomedical Research Centre Cambridge
6 · The paper itself

Abstract

We tested the hypothesis that the lipid composition of infant formula is consistent between manufacturers, countries and target demographic. We developed techniques to profile the lipid and glyceride fraction of milk and formula in a high throughput fashion. Formula from principal brands in the UK (2017-2019; bovine-, caprine-, soya-based), the Netherlands (2018; bovine-based) and South Africa (2018; bovine-based) were profiled along with fresh British animal and soya milk and skimmed milk powder. We found that the lipid and glyceride composition of infant formula differed by region, manufacturer and date of manufacture. The formulations within some brands, aimed at different target age ranges, differed considerably where others were similar across the range. Soya lecithin and milk lipids had characteristic phospholipid profiles. Particular sources of fat, such as coconut oil, were also easy to distinguish. Docosahexaenoic acid is typically found in triglycerides rather than phospholipids in formula. The variety by region, manufacturer, date of manufacture and sub-type for target demographics lead to an array of lipid profiles in formula. This makes it impossible to predict its molecular profile. Without detailed profile of the formula fed to infants, it is difficult to characterise the relationship between infant nutrition and their growth and development.

Indexed as

Food AnalysisAge FactorsChild DevelopmentGlyceridesHigh-Throughput Screening AssaysHumansInfantInfant FormulaInfant, NewbornInfant Nutritional Physiological PhenomenaLipidsNutritive ValueQuality ControlGlyceridesLipidsinfant developmentinfant nutritionlipid metabolismLipidomics

Identifiers

PMID31137537
PMCPMC6567151
OpenAlexW2945017478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.