ArticleNanomedicine : nanotechnology, biology, and medicine2019
Anti-biofilm activity of garlic extract loaded nanoparticles.
Article in Nanomedicine : nanotechnology, biology, and medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 59 citations in OpenAlex.
- Nature's Arsenal: Uncovering Antibacterial Agents Against Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- Aged garlic attenuates neuroinflammation via modulating the NF-κB pathway: Insights from multi-omics analyses.Food & nutrition research · 2025Article
- Generalized Dermatitis Caused byCase reports in veterinary medicine · 2025Article
- Article
- Exploring Possible Ways to Enhance the Potential and Use of Natural Products through Nanotechnology in the Battle against Biofilms of Foodborne Bacterial Pathogens.Pathogens (Basel, Switzerland) · 2023Review
- Medicinal and therapeutic properties of garlic, garlic essential oil, and garlic-based snack food: An updated review.Frontiers in nutrition · 2023Review
- A Review of Biofilm Formation ofAntibiotics (Basel, Switzerland) · 2022Review
- Evaluation of lyophilized royal jelly and garlic extract emulgels using a murine model infected with methicillin-resistant Staphylococcus aureus.AMB Express · 2022Article
- Nanoparticle, a promising therapeutic strategy for the treatment of infective endocarditis.Anatolian journal of cardiology · 2022Review
- Demonstration ofMolecules (Basel, Switzerland) · 2021Article
- Garlic (Antioxidants (Basel, Switzerland) · 2021Review
- Caffeine-loaded gold nanoparticles: antibiofilm and anti-persister activities against pathogenic bacteria.Applied microbiology and biotechnology · 2021Article
- Anacardic acid encapsulated solid lipid nanoparticles for Staphylococcus aureus biofilm therapy: chitosan and DNase coating improves antimicrobial activity.Drug delivery and translational research · 2021Article
- Strategies for Interfering With Bacterial Early Stage Biofilms.Frontiers in microbiology · 2021Review
- Antibacterial Properties of Organosulfur Compounds of Garlic (Frontiers in microbiology · 2021Review
- NOJournal of fungi (Basel, Switzerland) · 2020Article
- Garlic extract in prosthesis-related infections: a literature review.The Journal of international medical research · 2020Review
- Nitric oxide-loaded nano- and microparticle platforms serving as potential new antifungal therapeutics.Fungal biologyArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The emergence and widespread distribution of multi-drug resistant bacteria are considered as a major public health concern. The inabilities to curb severe infections due to antibiotic resistance have increased healthcare costs as well as patient morbidity and mortality. Bacterial biofilms formed by drug-resistant bacteria add additional challenges to treatment. This study describes a solgel based nanoparticle system loaded with garlic extract (GE-np) that exhibits: i) slow and sustained release of garlic components; ii) stabilization of the active components; and iii) significant enhancement of antimicrobial and antibiofilm activity relative to the free garlic extract. Also, GE-np were efficient in penetrating and disrupting the well-established methicillin-resistant Staphylococcus aureus (MRSA) biofilms. Overall, the study suggests that GE-np might be a promising candidate for the treatment of chronic infections due to biofilm forming drug-resistant bacteria.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.