Evidence map›Paper›PMID 30770539›Full record

Trial reportThe Journal of nutrition2019

Exposure to a Slightly Sweet Lipid-Based Nutrient Supplement During Early Life Does Not Increase the Preference for or Consumption of Sweet Foods and Beverages by 4-6-y-Old Ghanaian Preschool Children: Follow-up of a Randomized Controlled Trial.

Harriet Okronipa, Mary Arimond, Rebecca R Young, Charles D Arnold, Seth Adu-Afarwuah, Solace M Tamakloe, Helena J Bentil, Maku E Ocansey, Sika M Kumordzie, Brietta M Oaks and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00970866 (Efficacy of Lipid-based Nutrient Supplements), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00970866 nacompletednot on this map

Efficacy of Lipid-based Nutrient Supplements (LNS) for Pregnant and Lactating Women and Their Infants

TypeinterventionalSponsorUniversity of California, DavisRan2009 to 2017Enrolled3,499ConditionsAnemia, Malnutrition, StuntingArmsIron and Folic Acid (IFA), Multiple Micronutrient (MMN) group, Lipid-based Nutrient Supplements (LNS) group
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Harriet OkronipaProgram in International and Community Nutrition, Department of Nutrition, University of California, Davis, CA.
Mary ArimondIntake - Center for Dietary Assessment, FHI 360, Washington, DC.
Rebecca R YoungProgram in International and Community Nutrition, Department of Nutrition, University of California, Davis, CA.
Charles D ArnoldProgram in International and Community Nutrition, Department of Nutrition, University of California, Davis, CA.
Seth Adu-AfarwuahDepartment of Nutrition and Food Science, University of Ghana, Legon, Ghana.
Solace M TamakloeDepartment of Nutrition and Food Science, University of Ghana, Legon, Ghana.
Helena J BentilDepartment of Nutrition and Food Science, University of Ghana, Legon, Ghana.
Maku E OcanseyProgram in International and Community Nutrition, Department of Nutrition, University of California, Davis, CA.
Sika M KumordzieProgram in International and Community Nutrition, Department of Nutrition, University of California, Davis, CA.
Brietta M OaksDepartment of Nutrition and Food Sciences, University of Rhode Island, Kingston, RI.
Kathryn G DeweyProgram in International and Community Nutrition, Department of Nutrition, University of California, Davis, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether consuming sweet foods early in life affects sweet food preferences and consumption later in childhood is unknown.

objectiveWe tested the hypothesis that exposure to a slightly sweet lipid-based nutrient supplement (LNS) early in life would not increase preference for or consumption of sweet items at preschool age.

methodsWe followed up children who had participated in a randomized trial in Ghana in which LNS was provided to 1 group of women during pregnancy and 6 mo postpartum and to their infants from ages 6-18 mo (LNS group). The control group (non-LNS group) received iron and folic acid during pregnancy or multiple micronutrients during pregnancy and 6 mo postpartum, with no infant supplementation. At 4-6 y, we obtained data from caregivers on children's food and beverage preferences and consumption (n = 985). For a randomly selected subsample (n = 624), we assessed preference for sweet items using a photo game (range in potential scores, 0-15). For the photo game and reported consumption of sweet items, we examined group differences using predetermined noninferiority margins equivalent to an effect size of 0.2.

resultsMedian (quartile 1, quartile 3) reported consumption of sweet items (times in previous week) was 14 (8, 23) in the LNS group and 16 (9, 22) in the non-LNS group; in the photo game, the number of sweet items selected was 15 (11, 15) and 15 (11, 15), respectively. The upper level of the 95% CI of the mean difference between LNS and non-LNS groups did not exceed the noninferiority margins for these outcomes. Caregiver-reported preferences for sweet items also did not differ between groups (P = 0.9).

conclusionIn this setting, where child consumption of sweet foods was common, exposure to a slightly sweet LNS early in life did not increase preference for or consumption of sweet foods and beverages at preschool age. This trial was registered at clinicaltrials.gov as NCT00970866.

Indexed as

BeveragesFood PreferencesSweetening AgentsChildChild, PreschoolDietary SupplementsFemaleFollow-Up StudiesGhanaHumansInfantMaleMaternal Nutritional Physiological PhenomenaSweetening AgentschildrenconsumptionGhanalipid-based nutrient supplementspreferencesugar-sweetened beveragesweet food

Identifiers

PMID30770539
PMCPMC6398382

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.