Evidence map›Paper›PMID 30689122›Full record

ReviewCurrent allergy and asthma reports2019

Influence of the Maillard Reaction on the Allergenicity of Food Proteins and the Development of Allergic Inflammation.

Masako Toda, Michael Hellwig, Thomas Henle, Stefan Vieths

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
  6. Article
  7. Review
  8. Review
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  11. Article
  12. Oleosin Cor a 15 is a novel allergen for Italian hazelnut allergic children.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. 5-HMF induces anaphylactoid reactionsToxicology reports · 2020
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Masako TodaLaboratory of Food and Biomolecular Science, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan. masako.toda.a7@tohoku.ac.jp.
Michael HellwigChair of Food Chemistry, Technische Universität Dresden, Dresden, Germany.
Thomas HenleChair of Food Chemistry, Technische Universität Dresden, Dresden, Germany.
Stefan ViethsResearch Group "Molecular Allergology", Paul-Ehrlich-Institut, Langen, Germany.
TU Dresden · DEPaul Ehrlich Institut · DETohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe Maillard reaction (MR) is a non-enzymatic reaction between reducing sugars and compounds with free amino groups such as proteins and takes place during thermal processing and storage of foods. This review aims to discuss potential effects of dietary MR products on the pathological mechanisms of allergic diseases. RECENT

findingsSince the MR leads to modification of proteins with various types of glycation structures, the impact of the MR on the immunogenicity and potential allergenicity of food proteins in many allergenic foods has been assessed. In addition, recent studies have suggested that the MR products, in particular "advanced glycation end products (AGEs)," contained in the diet may be involved in the development of chronic inflammation by acting as inflammatory components and affecting the gut microbiome. This review found that the biological, immunological, and allergic properties of dietary MR products are diverse due to the complexity of the MR.

Indexed as

Maillard ReactionAllergensFood HypersensitivityGastrointestinal MicrobiomeGlycation End Products, AdvancedHumansInflammationAllergensGlycation End Products, AdvancedAdvanced glycation end products (AGEs)Food allergensGut microbiomeMaillard reactionPattern recognition receptors

Identifiers

PMID30689122
OpenAlexW2912500526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.