Evidence map›Paper›PMID 30461693›Full record

GuidelineObstetrics and gynecology2018

ACOG Practice Bulletin No. 201: Pregestational Diabetes Mellitus.

American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Obstetrics

9 registry-linked trialsAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Obstetrics and gynecology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 9 registered trials, which are not on this map. Cited by 189 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
189citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06064669 narecruitingstarted 2024, after this paper: background citation

Effect of Metformin on Healthy Live Birth After In-vitro Fertilization in Women With Prediabetes Mellitus: a Multicenter Double-blind Placebo Controlled Randomized Trial

Ran2024Enrolled988Registered outcomes26Posted comparisons0ConditionsIn-Vitro Fertilization, Metformin, PrediabetesArmsMetformin pretreatment before endometrial preparation for frozen embryo transfer, Metformin pretreatment before ovarian stimulation, Placebo pretreatment before endometrial preparation for frozen embryo transfer, Placebo pretreatment before ovarian stimulation
Open the trial in the graph
NCT03912363 nacompletednot on this mapstarted 2019, after this paper: background citation

Intrapartum Glycemic Control With Insulin Infusion Versus Rotating Fluids: Randomized Controlled Trial (RCT)

TypeinterventionalSponsorGeisinger ClinicRan2019 to 2025Enrolled114ConditionsType II Diabetes Mellitus, Gestational Diabetes MellitusArmsRotating fluids protocol, Insulin infusion protocol
NCT04542148 phase2active not recruitingnot on this mapstarted 2022, after this paper: background citation

Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes (Close the GAP)

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2022 to 2026Enrolled120ConditionsDiabetes Mellitus, Type 2, Preterm Birth, Pregnancy, High Risk, Diabetes, GestationalArmsSliding Scale Insulin, Up-Titration of Home Insulin, Continuous Insulin Infusion, Dexcom G6 Professional Continuous Glucose Monitor
NCT05305326 unknown statusnot on this mapstarted 2021, after this paper: background citation

Telocytes in Placental Tissues of Patients With Gestational and Pre-gestational Diabetes

TypeobservationalSponsorSohag UniversityRan2021 to 2022Enrolled60ConditionsDiabetes in Pregnancy
NCT06619301 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

Randomized Controlled Trial of Glargine Versus Neutral Protamine Hagedorn Insulin for the Treatment of Diabetes Mellitus in Pregnancy

TypeinterventionalSponsorLoyola UniversityRan2024 to 2027Enrolled160ConditionsDiabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM), Gestational Diabetes Mellitus, Class A2ArmsInsulin glargine, insulin NPH
NCT06643351 nacompletednot on this mapstarted 2024, after this paper: background citation

Intrapartum Maternal Glucose Control and Effect on Neonatal Hypoglycemia

TypeinterventionalSponsorUniversity of PittsburghRan2024 to 2026Enrolled169ConditionsGestational Diabetes Mellitus in Pregnancy, Pregestational Diabetes Mellitus, Neonatal HypoglycemiaArmsStandard Intrapartum Glucose Target Range, Liberalized Intrapartum Glucose Target Range
NCT07224893 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Once-Daily Versus Twice-Daily Insulin Glargine in the Management of Patients With Pregestational Diabetes Requiring Insulin

TypeinterventionalSponsorEastern Virginia Medical SchoolRan2026 to 2027Enrolled200ConditionsPregestational Diabetes, PregnancyArmsUse of insulin glargine once daily, Use of insulin glargine twice daily
NCT07250698 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Postprandial Walks for Glucose Control in Type 2 Diabetes in Pregnancy

TypeinterventionalSponsorEastern Virginia Medical SchoolRan2025 to 2026Enrolled40ConditionsPregestational Diabetes, Type 2 DiabetesArmsExercise
NCT07420972 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Pilot Study of Intrapartum Insulin Pump Use: Feasibility, Efficacy and Safety

TypeinterventionalSponsorMedstar Health Research InstituteRan2026 to 2028Enrolled30ConditionsDiabetes, Diabetes (Insulin-requiring, Type 1 or Type 2), PregnancyArmsInsulin pump
3 · Its place in the literature

Who cites it

189 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Maternal diabetes as a prenatal risk factor for multiple sclerosis in offspring: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Guideline
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Pooled it
  7. Effect of maternal diabetes on fetal heart function on echocardiography: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2021
    Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Can maternal metformin protect the developing fetal brain?American journal of obstetrics and gynecology · 2026
    Trial
  12. Trial
  13. Trial
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  15. Trial
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

129 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

American College of Obstetricians and Gynecologists' Committee on Practice Bulletins—Obstetrics

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregestational diabetes mellitus represents one of the most challenging medical complications of pregnancy because of the need for frequent monitoring and adjustment of medications as well as the potential for maternal and fetal complications. This document provides an overview of the current understanding of pregestational diabetes mellitus and suggests management guidelines during pregnancy. Because few well-designed studies have been performed, many of the guidelines are based on expert and consensus opinion. This document has been updated to reflect current data on pregestational diabetes. This Practice Bulletin is updated with summary information to counsel and manage women with pregestational diabetes before and during pregnancy, more recent literature reflecting experience with continuous subcutaneous insulin infusion during pregnancy, an expanded section on the role of oral hypoglycemic agents in pregnancy, and the option of long-acting reversible contraception during the postpartum period.

Indexed as

Blood GlucoseDelivery, ObstetricDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic KetoacidosisDiabetic NephropathiesDiabetic RetinopathyDietDirective CounselingExerciseFemaleFetal DiseasesHumansHypoglycemic AgentsInsulinsPregnancyBlood GlucoseHypoglycemic AgentsInsulins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 3 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.