Evidence map›Paper›PMID 30301241›Full record

Trial reportNutrients2018

Acute Effects of Substitution, and Addition, of Carbohydrates and Fat to Protein on Gastric Emptying, Blood Glucose, Gut Hormones, Appetite, and Energy Intake.

Caroline Giezenaar, Kylie Lange, Trygve Hausken, Karen L Jones, Michael Horowitz, Ian Chapman, Stijn Soenen

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

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  7. Preoperative fasting guidelines: A narrative review.European journal of anaesthesiology and intensive care · 2026
    Review
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  12. The Metabolic Syndrome, a Human Disease.International journal of molecular sciences · 2024
    Review
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  14. The [Lipids · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Caroline GiezenaarAdelaide Medical School and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide 5000, Australia. caroline.giezenaar@adelaide.edu.au.ORCID 0000-0001-5612-1918
Kylie LangeAdelaide Medical School and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide 5000, Australia. kylie.lange@adelaide.edu.au.
Trygve HauskenDepartment of Medicine, Haukeland University Hospital, 5021 Bergen, Norway. trygve.hausken@helse-bergen.no.
Karen L JonesAdelaide Medical School and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide 5000, Australia. karen.jones@adelaide.edu.au.ORCID 0000-0002-1155-5816
Michael HorowitzAdelaide Medical School and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide 5000, Australia. michael.horowitz@adelaide.edu.au.
Ian ChapmanAdelaide Medical School and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide 5000, Australia. ian.chapman@adelaide.edu.au.
Stijn SoenenAdelaide Medical School and National Health and Medical Research Council of Australia (NHMRC) Centre of Research Excellence (CRE) in Translating Nutritional Science to Good Health, The University of Adelaide, Adelaide 5000, Australia. stijn.soenen@adelaide.edu.au.
National Health and Medical Research Council · AURoyal Adelaide Hospital · AUHaukeland University Hospital · NO

Funding

Royal Adelaide Hospital Clinical Project Grant 1753Royal Adelaide Hospital Florey Fellowship 2129University of Adelaide Beacon Research Fellowship 104641
6 · The paper itself

Abstract

Whey protein, when ingested on its own, load-dependently slows gastric emptying and stimulates gut hormone concentrations in healthy young men. The aim of this study was to determine the effects of substitution, and addition, of carbohydrate (dextrose) and fat (olive oil) to whey protein. In randomized, double-blind order, 13 healthy young men (age: 23 ± 1 years, body mass index: 24 ± 1 kg/m²) ingested a control drink (450 mL; ~2 kcal/'control') or iso-volumetric drinks containing protein/carbohydrate/fat: (i) 14 g/28 g/12.4 g (280 kcal/'M

Indexed as

AppetiteGastric EmptyingAdolescentAdultBeveragesBlood GlucoseBody Mass IndexCholecystokininDietDietary CarbohydratesDietary FatsDietary ProteinsDouble-Blind MethodEnergy IntakeGastrointestinal HormonesGhrelinBlood GlucoseCholecystokininDietary CarbohydratesDietary FatsDietary ProteinsGastrointestinal HormonesGhrelinGlucagon-Like Peptide 1InsulinWhey Proteinsappetiteblood glucosegastric emptyinggut hormoneswhey protein

Identifiers

PMID30301241
PMCPMC6213197
OpenAlexW2894717756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.