Evidence map›Paper›PMID 30279384›Full record

ReviewNutrients2018

A Review on the Gluten-Free Diet: Technological and Nutritional Challenges.

Dalia El Khoury, Skye Balfour-Ducharme, Iris J Joye

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 1 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 1 synthesis or guideline pooled it, 295 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Gluten-Free Cakes WithFood science & nutrition · 2026
    Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Celiac Disease: Beyond Diet and Food Awareness.Foods (Basel, Switzerland) · 2025
    Review
  16. Article
  17. Article
  18. Foods (Basel, Switzerland) · 2024
    Review
  19. Review
  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dalia El KhouryDepartment of Family Relations & Applied Nutrition, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada. delkhour@uoguelph.ca.
Skye Balfour-DucharmeDepartment of Family Relations & Applied Nutrition, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada. balfourd@uoguelph.ca.
Iris J JoyeDepartment of Food Science, University of Guelph, 50 Stone Road East, Guelph, ON N1G 2W1, Canada. ijoye@uoguelph.ca.
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consumers, food manufacturers and health professionals are uniquely influenced by the growing popularity of the gluten-free diet. Consumer expectations have urged the food industry to continuously adjust and improve the formulations and processing techniques used in gluten-free product manufacturing. Health experts have been interested in the nutritional adequacy of the diet, as well as its effectiveness in managing gluten-related disorders and other conditions. In this review, we aim to provide a clear picture of the current motivations behind the use of gluten-free diets, as well as the technological and nutritional challenges of the diet as a whole. Alternative starches and flours, hydrocolloids, and fiber sources were found to play a complex role in mimicking the functional and sensory effects of gluten in gluten-free products. However, the quality of gluten-free alternatives is often still inferior to the gluten-containing products. Furthermore, the gluten-free diet has demonstrated benefits in managing some gluten-related disorders, though nutritional imbalances have been reported. As there is limited evidence supporting the use of the gluten-free diet beyond its role in managing gluten-related disorders, consumers are urged to be mindful of the sensorial limitations and nutritional inadequacies of the diet despite ongoing strategies to improve them.

Indexed as

Diet, Gluten-FreeCeliac DiseaseDietary FiberFlourGlutensHumansNutritional StatusNutritive ValueDietary FiberGlutensauto-immune diseaseceliac diseaseglutengluten-freegluten-related disordersnon-celiac gluten sensitivitynutritional adequacyproduct developmentweight managementwheat

Identifiers

PMID30279384
PMCPMC6213115
OpenAlexW2895563400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.