ArticleScientific reports2018
Evidence of exposure of domestic pigs to Highly Pathogenic Avian Influenza H5N1 in Nigeria.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Influenza A and D Viruses in Non-Human Mammalian Hosts in Africa: A Systematic Review and Meta-Analysis.Viruses · 2021Pooled it
- Spatiotemporal distribution trends and driving factors of avian influenza in poultry in China.One health (Amsterdam, Netherlands) · 2026Article
- Multiplex serological profiling reveals diverse avian and mammalian influenza A virus exposure in swine.iScience · 2026Article
- Epidemiology and Risk Modelling of Influenza A Virus Within and Between Pig Herds in Northern Lao PDR.Transboundary and emerging diseases · 2026Article
- Molecular and ecological determinants of mammalian adaptability in avian influenza virus.Infection · 2025Review
- Highly Pathogenic Avian Influenza (H5N1) Clade 2.3.4.4b in Cattle: A Rising One Health Concern.Animals : an open access journal from MDPI · 2025Review
- Bibliometric analysis of highly pathogenic avian influenza research globally from 2003 to 2023.Germs · 2025Article
- Serological Evidence of Highly Pathogenic Avian Influenza (H5N1) in Invasive Wild Pigs in Western Canada.Transboundary and emerging diseases · 2025Article
- Emerging threats of HPAI H5N1 clade 2.3.4.4b in swine: knowledge gaps and the imperative for a One Health approach.Frontiers in veterinary science · 2025Review
- Review
- Drivers for a pandemic due to avian influenza and options for One Health mitigation measures.EFSA journal. European Food Safety Authority · 2024Article
- Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide.Emerging infectious diseases · 2024Review
- Influenza A Virus in Pigs in Senegal and Risk Assessment of Avian Influenza Virus (AIV) Emergence and Transmission to Human.Microorganisms · 2023Article
- Assessment on the efficacy of methods 2 to 5 and method 7 set out in Commission Regulation (EU) No 142/2011 to inactivate relevant pathogens when producing processed animal protein of porcine origin intended to feed poultry and aquaculture animals.EFSA journal. European Food Safety Authority · 2023Article
- Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b.Emerging infectious diseases · 2023Article
- The Evolution of Highly Pathogenic Avian Influenza A (H5) in Poultry in Nigeria, 2021-2022.Viruses · 2023Article
- Seroconversion of a Swine Herd in a Free-Range Rural Multi-Species Farm against HPAI H5N1 2.3.4.4b Clade Virus.Microorganisms · 2023Article
- Usutu virus: An emerging flavivirus with potential threat to public health in Africa: Nigeria as a case study.Frontiers in veterinary science · 2023Review
- Antiviral options and therapeutics against influenza: history, latest developments and future prospects.Frontiers in cellular and infection microbiology · 2023Review
- A systematic review of influenza A virus prevalence and transmission dynamics in backyard swine populations globally.Porcine health management · 2022Review
Corrections and comments
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Authors and funding
12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Avian influenza viruses (AIV) potentially transmit to swine as shown by experiments, where further reassortment may contribute to the generation of pandemic strains. Associated risks of AIV inter-species transmission are greater in countries like Nigeria with recurrent epidemics of highly pathogenic AI (HPAI) in poultry and significant pig population. Analysis of 129 tracheal swab specimens collected from apparently healthy pigs at slaughterhouse during presence of HPAI virus H5N1 in poultry in Nigeria for influenza A by RT-qPCR yielded 43 positive samples. Twenty-two could be determined by clade specific RT-qPCR as belonging to the H5N1 clade 2.3.2.1c and confirmed by partial hemagglutinin (HA) sequence analysis. In addition, 500 swine sera were screened for antibodies against influenza A virus nucleoprotein and H5 HA using competition ELISAs and hemagglutination inhibition (HI) tests. Serologically, 222 (44.4%) and 42 (8.4%) sera were positive for influenza A virus NP and H5 antibodies, respectively. Sera reacted to H5N1 and A/H1N1pdm09 strains by HI suggesting exposure of the Nigerian domestic pig population to these viruses. We report for the first time in Nigeria, exposure of domestic pigs to H5N1 virus. This poses potential public health and pandemic risk due to interspecies transmission of avian and human influenza viruses.
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