Evidence map›Paper›PMID 29581972›Full record

ArticleBioMed research international2018

Effect of Curcumin-Nanoemulsion Associated with Photodynamic Therapy in Cervical Carcinoma Cell Lines.

Renata Prandini Adum de Matos, Marilia Freitas Calmon, Camila Fernanda Amantino, Luisa Lina Villa, Fernando Lucas Primo, Antonio Claudio Tedesco, Paula Rahal

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Renata Prandini Adum de MatosInstitute of Biosciences, Humanities and Exact Sciences (IBILCE), Department of Biology, São Paulo State University (UNESP), Rua Cristóvão Colombo, 2265 Bairro Jardim Nazareth, 15054-010 São José do Rio Preto, SP, Brazil.
Marilia Freitas CalmonInstitute of Biosciences, Humanities and Exact Sciences (IBILCE), Department of Biology, São Paulo State University (UNESP), Rua Cristóvão Colombo, 2265 Bairro Jardim Nazareth, 15054-010 São José do Rio Preto, SP, Brazil.ORCID 0000-0001-5203-0103
Camila Fernanda AmantinoDepartment of Chemistry, Center of Nanotechnology and Tissue Engineering-Photobiology and Photomedicine Research Group, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Av. Bandeirantes 3900, Ribeirão Preto, SP 14040-901, Brazil.
Luisa Lina VillaCenter for Translational Research in Oncology, Instituto de Câncer do Estado de São Paulo (ICESP), Av. Dr. Arnaldo 251, 8° Andar, Bairro Cerqueira César, 01246-000 São Paulo, SP, Brazil.
Fernando Lucas PrimoFaculty of Pharmaceutical Sciences of Araraquara, Department of Bioprocess and Biotechnology, São Paulo State University (UNESP), Rodovia Araraquara/Jaú, Km 01, s/n, Campos Ville, 14800-903 Araraquara, SP, Brazil.
Antonio Claudio TedescoDepartment of Chemistry, Center of Nanotechnology and Tissue Engineering-Photobiology and Photomedicine Research Group, Faculty of Philosophy, Sciences and Letters of Ribeirão Preto, University of São Paulo, Av. Bandeirantes 3900, Ribeirão Preto, SP 14040-901, Brazil.
Paula RahalInstitute of Biosciences, Humanities and Exact Sciences (IBILCE), Department of Biology, São Paulo State University (UNESP), Rua Cristóvão Colombo, 2265 Bairro Jardim Nazareth, 15054-010 São José do Rio Preto, SP, Brazil.ORCID 0000-0001-5693-6148
Universidade de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BRInstituto do Câncer do Estado de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is the fourth cause of cancer death in women. Curcumin has antineoplastic properties. Furthermore, curcumin may be used as a photosensitizing agent in Photodynamic Therapy. This study aimed to investigate the effects of Photodynamic Therapy in cellular viability using curcumin-nanoemulsion as a photosensitizing drug in cervical carcinoma cell lines. The empty nanoemulsion presented very low cytotoxicity in all cell lines analyzed. Additionally, the incubation with curcumin-nanoemulsion at 20

Indexed as

Caspase 3Caspase 7Cell Line, TumorCurcuminEmulsionsFemaleHumansNeoplasm ProteinsPhotochemotherapyUterine Cervical NeoplasmsCASP3 protein, humanCASP7 protein, humanCaspase 3Caspase 7CurcuminEmulsionsNeoplasm Proteins

Identifiers

PMID29581972
PMCPMC5822824
OpenAlexW2784693016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.