Evidence map›Paper›PMID 29388083›Full record

ArticleAnnals of nuclear medicine2018

Tatsuya Higashi, Ryuichi Nishii, Shinya Kagawa, Yoshihiko Kishibe, Masaaki Takahashi, Tomoko Okina, Norio Suzuki, Hiroshi Hasegawa, Yasuhiro Nagahama, Koichi Ishizu and 6 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Annals of nuclear medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. A brief history of Aβ imaging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  4. Imaging of cardiac amyloidosis using dynamicAnnals of nuclear medicine · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. American journal of nuclear medicine and molecular imaging · 2018
    Review
  17. World journal of nuclear medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Tatsuya HigashiShiga Medical Center Research Institute, Moriyama, Japan. higashi.tatsuya@qst.go.jp.ORCID http://orcid.org/0000-0002-8338-4737
Ryuichi NishiiShiga Medical Center Research Institute, Moriyama, Japan.
Shinya KagawaShiga Medical Center Research Institute, Moriyama, Japan.
Yoshihiko KishibeShiga Medical Center Research Institute, Moriyama, Japan.
Masaaki TakahashiShiga Medical Center Research Institute, Moriyama, Japan.
Tomoko OkinaDepartment of Geriatric Medicine, Shiga General Hospital, Moriyama, Japan.
Norio SuzukiDepartment of Geriatric Medicine, Shiga General Hospital, Moriyama, Japan.
Hiroshi HasegawaDepartment of Geriatric Medicine, Shiga General Hospital, Moriyama, Japan.
Yasuhiro NagahamaKawasaki Memorial Hospital, Kawasaki, Japan.
Koichi IshizuShiga Medical Center Research Institute, Moriyama, Japan.
Naoya OishiResearch and Educational Unit of Leaders for Integrated Medical System, Center for the Promotion of Interdisciplinary Education and Research, Kyoto University, Kyoto, Japan.
Hiroyuki KimuraDepartment of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto, Japan.
Hiroyuki WatanabeDepartment of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Masahiro OnoDepartment of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Hideo SajiDepartment of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.
Hiroshi YamauchiShiga Medical Center Research Institute, Moriyama, Japan.
Shiga Medical Center · JPKyoto University · JPNational Institutes for Quantum Science and Technology · JPKawasaki Hospital · JPKyoto Pharmaceutical University · JP

Funding

Japan Society for the Promotion of Science NEXT Program, LS060
6 · The paper itself

Abstract

objectiveRecently, we developed a benzofuran derivative for the imaging of β-amyloid plaques, 5-(5-(2-(2-(2-

methods61 healthy volunteers (age: 53.7 ± 13.1 years old; 19 male and 42 female; age range 24-79) and 55 patients with suspected dementia [Alzheimer's Disease (AD); early AD: n = 19 and moderate stage AD: n = 8, other dementia: n = 9, mild cognitive impairment (MCI): n = 16, cognitively normal: n = 3] for first clinical study underwent static head PET/CT scan using

resultsStudies with healthy volunteers showed that

conclusionsOur first clinical study suggest that

Indexed as

Positron Emission Tomography Computed TomographyRadiopharmaceuticalsAdultAgedAged, 80 and overAmyloid beta-PeptidesAniline CompoundsBenzothiazolesBrainCognitive DysfunctionDementiaFemaleHumansMaleMiddle AgedThiazoles2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazoleAmyloid beta-PeptidesAniline CompoundsBenzothiazolesRadiopharmaceuticalsThiazolesAlzheimer diseaseAmyloid imagingHealthy volunteersPositron emission tomography

Identifiers

PMID29388083
PMCPMC5852179
OpenAlexW2794184137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.