Evidence map›Paper›PMID 29368511›Full record

ArticleBiochemistry2018

Peptidoglycan Compositional Analysis of Enterococcus faecalis Biofilm by Stable Isotope Labeling by Amino Acids in a Bacterial Culture.

James D Chang, Ashley G Wallace, Erin E Foster, Sung Joon Kim

Abstract read
In one paragraph

Article in Biochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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  4. Article
  5. Article
  6. Chemical science · 2024
    Article
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  8. Article
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  10. Review
  11. Review
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  16. mBio · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

James D ChangDepartment of Chemistry and Biochemistry, Baylor University , Waco, Texas 76798, United States.
Ashley G WallaceDepartment of Chemistry and Biochemistry, Baylor University , Waco, Texas 76798, United States.
Erin E FosterDepartment of Chemistry and Biochemistry, Baylor University , Waco, Texas 76798, United States.
Sung Joon KimDepartment of Chemistry and Biochemistry, Baylor University , Waco, Texas 76798, United States.ORCID 0000-0002-2007-6606
Baylor University · US

Funding

GLYCOPEPTIDE COMPLEXES WITH BACTERIAL CELL WALLS BY REDORR01GM116130 · NIGMS · WASHINGTON UNIVERSITY · PI PATTI, GARY J · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM116130
6 · The paper itself

Abstract

Peptidoglycan (PG) is a major component of the cell wall in Enterococcus faecalis. Accurate analysis of PG composition provides crucial insights into the bacterium's cellular functions and responses to external stimuli, but this analysis remains challenging because of various chemical modifications to PG-repeat subunits. We characterized changes to the PG composition of E. faecalis grown as planktonic bacteria and biofilm by developing "stable isotope labeling by amino acids in bacterial culture" (SILAB), optimized for bacterial cultures with incomplete amino acid labeling. This comparative analysis by mass spectrometry was performed by labeling E. faecalis in biofilm with heavy Lys (l-[

Indexed as

BiofilmsAcetylationAmino AcidsCell WallEndopeptidasesEnterococcus faecalisIsotope LabelingPeptidoglycanPlanktonSpectrometry, Mass, Electrospray IonizationAmino AcidsEndopeptidasesmutanolysinPeptidoglycan

Identifiers

PMID29368511
PMCPMC5972391
OpenAlexW2785017462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.