Evidence map›Paper›PMID 29319880›Full record

ArticleJournal of the American Geriatrics Society2018

Competing Risks of Fracture and Death in Older Adults with Chronic Kidney Disease.

Rasheeda K Hall, Richard Sloane, Carl Pieper, Courtney Van Houtven, Joanne LaFleur, Robert Adler, Cathleen Colón-Emeric

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Osteoporosis in Patients with Chronic Kidney Diseases: A Systemic Review.International journal of molecular sciences · 2020
    Pooled it
  2. The association between chronic kidney disease, falls, and fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
  3. Glycemic Control and Insulin Treatment Alter Fracture Risk in Older Men With Type 2 Diabetes Mellitus.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019 · on this map
    Trial
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  11. The risk of new fragility fractures in patients with chronic kidney disease and hip fracture-a population-based cohort study in the UK.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  12. Acetylcholinesterase Inhibitors Are Associated with Reduced Fracture Risk among Older Veterans with Dementia.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020
    Article
  13. Article
  14. Chronic kidney disease is associated with low BMD at the hip but not at the spine.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Rasheeda K HallGeriatric Research, Education and Clinical Center, Durham Veterans Affairs, Durham, North Carolina.ORCID 0000-0002-3057-4828
Richard SloaneDivision of Geriatrics, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Carl PieperDepartment of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina.
Courtney Van HoutvenHealth Services Research and Development, Durham Veterans Affairs, Durham, North Carolina.
Joanne LaFleurDepartment of Pharmacotherapy, University of Utah, Salt Lake City, Utah.
Robert AdlerHunter Holmes McGuire Veterans Affairs Medical Center, Richmond, Virginia.
Cathleen Colón-EmericGeriatric Research, Education and Clinical Center, Durham Veterans Affairs, Durham, North Carolina.
Health Services Research & Development · USDuke Medical Center · USDuke University · USGeriatric Research Education and Clinical Center · USUniversity of Utah · USVirginia Commonwealth University · US

Funding

Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
Duke CTSA (Composite)KL2TR001115 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, KRAFT, MONICA · 2013 to 2017
$5.1M
Mentoring Intervention Development in Fall and Fracture PreventionK24AG049077 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S · 2015 to 2019
$361k
Improving Quality of Life Measurement in Older Dialysis PatientsR03AG050834 · NIA · DUKE UNIVERSITY · PI HALL, RASHEEDA K · 2015 to 2016
$239k
NCATS NIH HHS KL2 TR001115NCATS NIH HHS UL1 TR001117NIA NIH HHS K24 AG049077NIA NIH HHS P30 AG028716NIA NIH HHS R03 AG050834NIDDK NIH HHS L30 DK115059
6 · The paper itself

Abstract

objectivesTo examine whether chronic kidney disease (CKD) at any stage is associated with fracture risk after adjusting for competing mortality and to determine whether age or race modify the relationship between CKD and fracture risk.

designProspective cohort study.

settingDepartment of Veterans Affairs (VA) national healthcare system.

participantsMen receiving VA primary care aged 65 and older with no history of fracture or osteoporosis therapy (N = 712, 918). MEASUREMENTS: We determined CKD stage from baseline estimated glomerular filtration rate (eGFR). Participants were followed for up to 10 years for occurrence of any fracture or death. We ascertained fractures and covariates from VA medical records and Medicare claims.

resultsOf the 356,459 older veterans with CKD (defined as eGFR <60 mL/min per 1.73 m

conclusionsIn older male veterans, CKD, including Stage 3, is associated with a moderately greater fracture risk irrespective of age, race, or bone mineral density.

Indexed as

AgedBone DensityComorbidityDisease ProgressionFractures, BoneGlomerular Filtration RateHumansMaleMiddle AgedOsteoporosisProspective StudiesRenal Insufficiency, ChronicRisk AssessmentUnited StatesVeteranscompeting risksgeriatric nephrologyosteoporosis

Identifiers

PMID29319880
PMCPMC5849495
OpenAlexW2782767510

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.