Evidence map›Paper›PMID 28808398›Full record

ArticlePharmacognosy magazine2017

Mechanism of Action of Isolated Caffeic Acid and Epicatechin 3-gallate from

Shanmugapriya Perumal, Roziahanim Mahmud, Sabariah Ismail

Abstract read
In one paragraph

Article in Pharmacognosy magazine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
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  16. Review
  17. Review
  18. Antibiotics (Basel, Switzerland) · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shanmugapriya PerumalPharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Malaysia.
Roziahanim MahmudPharmaceutical Chemistry, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Malaysia.
Sabariah IsmailCentre for Herbal Standardization, Penang, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe escalating dominance of resistant

objectiveThe objective of this study is to address the biological targets and probable mechanisms of action underlying the potent antibacterial effect of the isolated compounds from MATERIALS AND

methodsThe action mechanisms of caffeic acid (CA) and epicatechin 3-gallate (ECG) on

resultsThe findings revealed that ECG and CA targeted both cell wall and cytoplasmic membrane of

conclusionThe overall study concludes that ECG and CA isolated from SUMMARY: Epicatechin 3-gallate (ECG) and caffeic acid (CA) exhibited remarkable bactericidal abilities by increasing the outer membrane and plasma membrane permeability of

Indexed as

ErythromycinEuphorbia hirta (L.)nucleotide leakagepotassium ion effluxrifampicin

Identifiers

PMID28808398
PMCPMC5538172

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.