Evidence map›Paper›PMID 28604884›Full record

ReviewMetallomics : integrated biometal science2017

Ferrous iron efflux systems in bacteria.

Hualiang Pi, John D Helmann

Open access · greenAbstract readReview
In one paragraph

Review in Metallomics : integrated biometal science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 95 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Microbial metal physiology: ions to ecosystems.Nature reviews. Microbiology · 2025
    Review
  5. Article
  6. Article
  7. Adaptations of the GenusCurrent issues in molecular biology · 2025
    Review
  8. Article
  9. Review
  10. Review
  11. Bacterial Organelles in Iron Physiology.Molecular microbiology · 2024
    Review
  12. TheJournal of bacteriology · 2024
    Article
  13. ThebioRxiv : the preprint server for biology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Microorganisms · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hualiang PiDepartment of Microbiology, Cornell University, Ithaca, NY 14853-8101, USA. jdh9@cornell.edu.
John D Helmann
Cornell University · US

Funding

Bacillus subtilis Stress ResponsesR35GM122461 · NIGMS · CORNELL UNIVERSITY · PI John D Helmann · 2017 to 2026
$7.6M
Zinc Homeostasis in Bacillus subtilisR01GM059323 · NIGMS · CORNELL UNIVERSITY ITHACA · PI HELMANN, JOHN D · 2000 to 2017
$4.5M
NIGMS NIH HHS R01 GM059323NIGMS NIH HHS R35 GM122461
6 · The paper itself

Abstract

Bacteria require iron for growth, with only a few reported exceptions. In many environments, iron is a limiting nutrient for growth and high affinity uptake systems play a central role in iron homeostasis. However, iron can also be detrimental to cells when it is present in excess, particularly under aerobic conditions where its participation in Fenton chemistry generates highly reactive hydroxyl radicals. Recent results have revealed a critical role for iron efflux transporters in protecting bacteria from iron intoxication. Systems that efflux iron are widely distributed amongst bacteria and fall into several categories: P

Indexed as

BacteriaBacterial ProteinsBiological TransportCell MembraneDiffusionIronBacterial ProteinsIron

Identifiers

PMID28604884
PMCPMC5675029
OpenAlexW2621969801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.