ArticleInternational journal of molecular sciences2017
Hazelnut (Corylus avellana L.) Shells Extract: Phenolic Composition, Antioxidant Effect and Cytotoxic Activity on Human Cancer Cell Lines.
Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 93 citations in OpenAlex.
- Use of Hazelnut Shells Subjected to Instant Controlled Pressure Drop (DIC) Treatment in Cakes: Physicochemical, Nutritional, Textural Properties, and Pore Structure Using Thresholding Algorithms.Journal of food science · 2026Article
- Technological Optimization and Antioxidant Efficacy via the NRF-2-Mediated Defense Pathway ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Impact of altitudinal variation on nutrient dynamics, and bioactive composition of hazelnut (Corylus avellana L.) kernel.BMC plant biology · 2026Article
- Interaction of Hazelnut-Derived Polyphenols with Biodegradable Film Matrix: Structural, Barrier, and Functional Properties.Foods (Basel, Switzerland) · 2025Article
- Research Progress on the Antioxidant Activity of Natural Diarylheptanoids: Mechanisms and Structure-activity Relationships.Current medicinal chemistry · 2025Review
- Inducing Effect of Corylus avellana on Cytotoxic Activity in Lung and Breast Cancer Cells via Apoptosis.Plant foods for human nutrition (Dordrecht, Netherlands) · 2024Article
- Non-Hereditary Obesity Type Networks and New Drug Targets: An In Silico Approach.International journal of molecular sciences · 2024Article
- Phenolic Compounds and Antioxidant Capacity Comparison of Wild-Type and Yellow-LeafPlants (Basel, Switzerland) · 2024Article
- Evaluation of the Chemical Stability, Membrane Permeability and Antiproliferative Activity of Cyclic Diarylheptanoids from European Hornbeam (International journal of molecular sciences · 2023Article
- Polymeric Patches Based on Chitosan/Green Clay Composites and Hazelnut Shell Extract as Bio-Sustainable Medication for Wounds.Pharmaceutics · 2023Article
- Study of the Apoptotic Impacts of Hazelnut Oil on the Colorectal Cancer Cell Line.Advanced biomedical research · 2023Article
- Potential Valorization of Edible Nuts By-Products: Exploring the Immune-Modulatory and Antioxidants Effects of Selected Nut Shells Extracts in Relation to Their Metabolic Profiles.Antioxidants (Basel, Switzerland) · 2022Article
- Therapeutic Potential of Natural Products in Treatment of Cervical Cancer: A Review.Nutrients · 2021Review
- Gallic Acid an Agricultural Byproduct Modulates the Biofilm Matrix Exopolysaccharides of the Phytopathogen Ralstonia solanacearum.Current microbiology · 2020Article
- Recovery of Bioactive Compounds from Hazelnuts and Walnuts Shells: Quantitative-Qualitative Analysis and Chromatographic Purification.Biomolecules · 2020Article
- Evaluating the Suitability of Hazelnut Skin as a Feed Ingredient in the Diet of Dairy Cows.Animals : an open access journal from MDPI · 2020Article
- Study onPharmaceutics · 2020Article
- Tetra-substituted pyrrole derivatives act as potent activators of p53 in melanoma cells.Investigational new drugs · 2020Article
- Chemical Composition, Total Phenols and Flavonoids Contents and Antioxidant Activity as Nutritive Potential of Roasted Hazelnut Skins (Foods (Basel, Switzerland) · 2020Article
- Design and Development of Spray-Dried Microsystems to Improve Technological and Functional Properties of Bioactive Compounds from Hazelnut Shells.Molecules (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hazelnut shells, a by-product of the kernel industry processing, are reported to contain high amount of polyphenols. However, studies on the chemical composition and potential effects on human health are lacking. A methanol hazelnut shells extract was prepared and dried. Our investigation allowed the isolation and characterization of different classes of phenolic compounds, including neolignans, and a diarylheptanoid, which contribute to a high total polyphenol content (193.8 ± 3.6 mg of gallic acid equivalents (GAE)/g of extract). Neolignans, lawsonicin and cedrusin, a cyclic diarylheptanoid, carpinontriol B, and two phenol derivatives, C-veratroylglycol, and β-hydroxypropiovanillone, were the main components of the extract (0.71%-2.93%,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.