ArticlePharmaceutical biology2017
In vitro digestion, antioxidant and antiacetylcholinesterase activities of two species of Ruta: Ruta chalepensis and Ruta montana.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- The In Vitro Pharmacokinetics of Medicinal Plants: A Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Exploring the Therapeutic Potential of Medicinal Plants in the Context of Gastrointestinal Health: A Review.Plants (Basel, Switzerland) · 2025Review
- Article
- Extraction of phenolic compounds fromFrontiers in nutrition · 2024Article
- Article
- Phenolic Characterization Using cLC-DAD Analysis and Evaluation of In Vitro and In Vivo Pharmacological Activities ofAntioxidants (Basel, Switzerland) · 2022Article
- Phytochemical Characterization, and Antioxidant and Antimicrobial Properties of Agitated Cultures of Three Rue Species:Antioxidants (Basel, Switzerland) · 2022Article
- The Doctrine of Signatures in Israel-Revision and Spatiotemporal Patterns.Plants (Basel, Switzerland) · 2021Article
- Phytochemical Screening and in-vitro Evaluation of Antibacterial Activities ofJournal of experimental pharmacology · 2021Article
- The Influence of In Vitro Gastrointestinal Digestion on the Chemical Composition and Antioxidant and Enzyme Inhibitory Capacities of Carob Liqueurs Obtained with Different Elaboration Techniques.Antioxidants (Basel, Switzerland) · 2019Article
- IN VIVO EFFECT OFAfrican journal of traditional, complementary, and alternative medicines : AJTCAM · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
contextRuta genus (Rutaceae) is abundantly used and described in the most ancient systematic records of medical practice of the Mediterranean world. In Tunisia, this genus is represented by two medicinal and aromatic shrubs: Ruta chalepensis L. and Ruta montana L.
objectiveThis study investigates the antioxidant and acetylcholinesterase inhibition (AChE) activities before and after in vitro gastrointestinal metabolism of leaf decoction of R. chalepensis and R. montana. MATERIALS AND
methodsWe study, in vitro, the effect of the gastrointestinal juices gastric (1.75 mL) or pancreatic (2.5 mL) juices, on the biological activity by the measurement of the antioxidant activity and AChE inhibition during 4 h of decoction extract obtained from the leaves of the two species of Ruta.
resultsThe results showed that the ability to inhibit the AChE enzyme was similar; being the greatest inhibitory activity exhibited by the ethanol extract (IC
conclusionIn conclusion, we showed that there was no appreciable degradation and that the activity was kept constant after gastric and pancreatic juice digestion.
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