Evidence map›Paper›PMID 27909891›Full record

ArticleThe journal of physiological sciences : JPS2017

Canola oil rich in oleic acid improves diastolic heart function in diet-induced obese rats.

Sijo Joseph Thandapilly, Pema Raj, Xavier Lieben Louis, Danielle Perera, Prasanga Yamanagedara, Peter Zahradka, Carla G Taylor, Thomas Netticadan

Open access · goldAbstract read
In one paragraph

Article in The journal of physiological sciences : JPS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sijo Joseph ThandapillyDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada.
Pema RajCanadian Centre for Agri-Food Research in Health and Medicine, Winnipeg, MB, Canada.
Xavier Lieben LouisDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada.
Danielle PereraCanadian Centre for Agri-Food Research in Health and Medicine, Winnipeg, MB, Canada.
Prasanga YamanagedaraCanadian Centre for Agri-Food Research in Health and Medicine, Winnipeg, MB, Canada.
Peter ZahradkaDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada.
Carla G TaylorDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, MB, Canada. ctaylor@sbrc.ca.
Thomas NetticadanAgriculture and Agri-Food Canada, Winnipeg, MB, Canada. tnetticadan@sbrc.ca.
Agriculture and Agri-Food Canada · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a leading cause of cardiovascular disease. It directly affects heart structure and function and contributes to heart failure. Diet is a major factor involved in the development of obesity along with genetic factors. We examined the effects of monounsaturated and polyunsaturated fatty acid-rich oils on cardiac structure and function in the diet-induced rodent model of obesity (DIO). Obese prone (OP) rats were fed a high-fat diet (HF; 55% of kcal) for 12 weeks; Sprague-Dawley rats fed commercial chow served as control. Echocardiography was performed to assess the cardiac structure and function in all rats at 12 weeks. OP rats fed the HF diet showed significant impairment in diastolic function compared to control rats. The HF diet containing high oleic canola oil significantly improved diastolic function of OP rats compared to the HF diet with lard. In conclusion, canola oil rich in oleic acid, when incorporated into an HF diet, prevents the development of diastolic dysfunction in DIO rats.

Indexed as

AnimalsDiet, High-FatHeartHeart Failure, DiastolicObesityOleic AcidPlant OilsRapeseed OilRatsRats, Sprague-DawleyOleic AcidPlant OilsRapeseed OilDiastolic dysfunctionDiet-induced obesityEdible oil

Identifiers

PMID27909891
PMCPMC10717867
OpenAlexW2558016691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.