Evidence map›Paper›PMID 27744546›Full record

ArticleEuropean journal of nutrition2018

Soy isoflavone intake and prevalence of depressive symptoms during pregnancy in Japan: baseline data from the Kyushu Okinawa Maternal and Child Health Study.

Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Shinya Furukawa, Masashi Arakawa

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
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  8. Isoflavones Mediate Dendritogenesis Mainly through Estrogen Receptor α.International journal of molecular sciences · 2023
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  20. Letter to the Editor.European journal of nutrition · 2017
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yoshihiro MiyakeDepartment of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Ehime, 791-0295, Japan. miyake.yoshihiro.ls@ehime-u.ac.jp.ORCID http://orcid.org/0000-0003-1244-4488
Keiko TanakaDepartment of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Ehime, 791-0295, Japan.
Hitomi OkuboDepartment of Health Promotion, National Institute of Public Health, Saitama, Japan.
Satoshi SasakiDepartment of Social and Preventive Epidemiology, School of Public Health, The University of Tokyo, Tokyo, Japan.
Shinya FurukawaDepartment of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Ehime, 791-0295, Japan.
Masashi ArakawaHealth Tourism Research Fields, Graduate School of Tourism Sciences, University of the Ryukyus, Okinawa, Japan.
Ehime Medical Center · JPNational Institute of Public Health · JPThe University of Tokyo · JPUniversity of the Ryukyus · JP

Funding

Japan Society for the Promotion of Science 19590606, 20791654, 21590673, 22592355, 22119507, 24390158, 25463275, and 25670305
6 · The paper itself

Abstract

objectiveSeveral observational studies and trials examined the relationship between isoflavones or soybeans and depressive symptoms among peri- and postmenopausal women. We cross-sectionally evaluated the associations between intake of soy products and isoflavones and depressive symptoms during pregnancy in Japan.

methodsStudy subjects were 1745 pregnant women. Dietary intake during the preceding month was assessed using a self-administered diet history questionnaire. Depressive symptoms were defined by a score of 16 or over in the Center for Epidemiologic Studies Depression Scale.

resultsHigher intake of total soy products, tofu, tofu products, fermented soybeans, boiled soybeans, miso soup, and isoflavones was independently related to a lower prevalence of depressive symptoms during pregnancy: The adjusted prevalence ratios (95 % confidence intervals, P for trend) between extreme quartiles were 0.63 (0.47-0.85, 0.002), 0.72 (0.54-0.96, 0.007), 0.74 (0.56-0.98, 0.04), 0.57 (0.42-0.76, <0.0001), 0.73 (0.55-0.98, 0.03), 0.65 (0.49-0.87, 0.003), and 0.63 (0.46-0.86, 0.002), respectively. A significant positive exposure-response relationship was found between miso intake and depressive symptoms during pregnancy. No material relationship was observed between soymilk intake and depressive symptoms during pregnancy.

conclusionsOur study is the first to show independent inverse relationships between intake of total soy products, tofu, tofu products, fermented soybeans, boiled soybeans, miso soup, and isoflavones and depressive symptoms during pregnancy.

Indexed as

DietFunctional FoodMaternal Nutritional Physiological PhenomenaSoy FoodsAdultCohort StudiesCross-Sectional StudiesDepressionDepressive DisorderFemaleFermented FoodsHumansIsoflavonesJapanNutrition SurveysPregnancyIsoflavonesDepressive symptomsIntakeIsoflavonesJapanesePregnancySoy

Identifiers

PMID27744546
OpenAlexW2531502452

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.