Evidence map›Paper›PMID 27730474›Full record

ReviewCurrent cardiology reports2016

Cardiovascular Complications of HIV in Endemic Countries.

Matthew J Feinstein, Milana Bogorodskaya, Gerald S Bloomfield, Rajesh Vedanthan, Mark J Siedner, Gene F Kwan, Christopher T Longenecker

Open access · greenAbstract readReview
In one paragraph

Review in Current cardiology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pitavastatin to Prevent Cardiovascular Disease in HIV Infection.The New England journal of medicine · 2023 · on this map
    Trial
  3. Cardiovascular Risk and Health Among People With Human Immunodeficiency Virus (HIV) Eligible for Primary Prevention: Insights From the REPRIEVE Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021 · on this map
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Matthew J FeinsteinDivision of Cardiovascular Diseases, Department of Medicine, Northwestern University Feinberg School of Medicine, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL, USA. Matthewjfeinstein@northwestern.edu.
Milana BogorodskayaDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Gerald S BloomfieldDivision of Cardiology, Department of Medicine, Duke Clinical Research Institute, Duke University, Durham, NC, USA.
Rajesh VedanthanZena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Mark J SiednerDivision of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Gene F KwanSection of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Christopher T LongeneckerDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Boston University · USCase Western Reserve University · USClinical Research Institute · USIcahn School of Medicine at Mount Sinai · USMassachusetts General Hospital · USNorthwestern University · USUniversity School · US

Funding

Behavioral Aspects of Low-cost Medical Devices to Improve HIV CareK23MH099916 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI SIEDNER, MARK J · 2013 to 2017
$917k
Pericardial fat, inflammation, and structural heart disease in HIVK23HL123341 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI LONGENECKER, CHRIS TODD · 2014 to 2018
$885k
NHLBI NIH HHS K23 HL123341NIMH NIH HHS K23 MH099916
6 · The paper itself

Abstract

Effective combination antiretroviral therapy (ART) has enabled human immunodeficiency virus (HIV) infection to evolve from a generally fatal condition to a manageable chronic disease. This transition began two decades ago in high-income countries and has more recently begun in lower income, HIV endemic countries (HIV-ECs). With this transition, there has been a concurrent shift in clinical and public health burden from AIDS-related complications and opportunistic infections to those associated with well-controlled HIV disease, including cardiovascular disease (CVD). In the current treatment era, traditional CVD risk factors and HIV-related factors both contribute to an elevated risk of myocardial infarction, stroke, heart failure, and arrhythmias. In HIV-ECs, the high prevalence of persons living with HIV and growing prevalence of CVD risk factors will contribute to a growing epidemic of HIV-associated CVD. In this review, we discuss the epidemiology and pathophysiology of cardiovascular complications of HIV and the resultant implications for public health efforts in HIV-ECs.

Indexed as

AIDS-Related Opportunistic InfectionsAnti-HIV AgentsCardiomyopathiesDrug Therapy, CombinationHeart FailureHIV InfectionsHumansMyocardial InfarctionPrevalenceRisk FactorsSmokingStrokeAnti-HIV AgentsCardiovascular epidemiologyGlobal healthHealth disparitiesHIVHuman immunodeficiency virusRisk factors

Identifiers

PMID27730474
PMCPMC6717318
OpenAlexW2531728887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.