← Statins × cardiovascular events

TrialThe New England journal of medicine2023

Pitavastatin to Prevent Cardiovascular Disease in HIV Infection.

Steven K Grinspoon et al.PubMed ↗Full text ↗Publisher ↗

The primary results report of NCT02344290. Its numbers are set against the trial’s posted results below.

What the trial testedrandomised · 7,769 people · 2023

Randomised comparison

Reduced cardiovascular events

Doesn’t vote: the registry posted this outcome, and its result counts

−35%−52% to −10%

Bigger than 8 in 10 for cardiovascular events

As reported

HR 0.65, 95% CI 0.48–0.90

Against the trial’s posted results

  • Same verdict as the posted result, different numberThis paper HR 0.65 (0.48–0.90)Posted, primary outcome HR 0.64 (0.48–0.84)Incidence Rate of Major Adverse Cardiovascular Event (MACE)Another analysis of the same outcome: a different population, model or data cut. The trial counts once.

One number in the abstract

the abstract, start to end

… in the placebo group (hazard ratio, 0.65; 95% confidence interval [CI], …

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
HR 0.650.48–0.90
StatinsCardiovascular events
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264 papers cite itlatest 60 shown

2023
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2024
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The trial

Full record →Abstract, authors, funding and every citing paper · PMID 37486775