Evidence map›Paper›PMID 27194895›Full record

ReviewJournal of clinical and experimental hepatology2016

Coffee and Liver Disease.

Manav Wadhawan, Anil C Anand

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of clinical and experimental hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. The Effects of Caffeine on Anxiety Behavior in Healthy Individuals: A Systematic Review of the Literature.Stress and health : journal of the International Society for the Investigation of Stress · 2026
    Pooled it
  2. Gluten's silent strike: Unmasking its impact on liver health.World journal of gastrointestinal pathophysiology · 2025
    Review
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  14. The Epigenetic Effects of Coffee.Molecules (Basel, Switzerland) · 2023
    Review
  15. Coffee-Derived Exosome-Like Nanoparticles: Are They the Secret Heroes?The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Manav WadhawanFortis Escorts Liver and Digestive Diseases Institute, Delhi, India.
Anil C AnandIndraprastha Apollo Hospital, Delhi, India.
Indraprastha Apollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coffee is the most popular beverage in the world. Consumption of coffee has been shown to benefit health in general, and liver health in particular. This article reviews the effects of coffee intake on development and progression of liver disease due to various causes. We also describe the putative mechanisms by which coffee exerts the protective effect. The clinical evidence of benefit of coffee consumption in Hepatitis B and C, as well as nonalcoholic fatty liver disease and alcoholic liver disease, has also been presented. Coffee consumption is associated with improvement in liver enzymes (ALT, AST, and GGTP), especially in individuals with risk for liver disease. Coffee intake more than 2 cups per day in patients with preexisting liver disease has been shown to be associated with lower incidence of fibrosis and cirrhosis, lower hepatocellular carcinoma rates, as well as decreased mortality.

Indexed as

CGA, chlorogenic acidcirrhosiscoffeefibrosishepatocellular carcinomaMEC, multiethnic cohortmortalityMRP, Maillard reaction productsNAFLDNAFLD, nonalcoholic fatty liver disease

Identifiers

PMID27194895
PMCPMC4862107
OpenAlexW2294579280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.