ArticlePlanta2016
Endophytes of opium poppy differentially modulate host plant productivity and genes for the biosynthetic pathway of benzylisoquinoline alkaloids.
Article in Planta, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 115 citations in OpenAlex.
- Characterization of culturable endophytes and microbial communities in the rhizosphere and pitcher fluid of the carnivorous plant Nepenthes khasiana.Archives of microbiology · 2026Article
- Ocotea odorifera extract: antimicrobial and antibiofilm activities, phytochemical aspects, cytotoxicity and anti-inflammatory potential of an endangered plant species.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Pharmacologically Important Metabolites from Viola spp and Role of Associated Endophytes in Reshaping its Metabolites Biosynthesis.Current microbiology · 2026Review
- Microbial elicitors to metabolic reprogramming: an integrative model of plant-microbe interactions.Frontiers in microbiology · 2026Review
- Endophyte diversity and its correlation with naphthoquinone metabolites in cultivated Arnebia euchroma across different growth years.PloS one · 2026Article
- Prospective of Indole-3-Acteic Acid (IAA) and Endophytic Microbe Bacillus subtilis Strain SSA4 in Paddy Seedlings Development and Ascorbate-Glutathione (AsA-GSH) Cycle Regulation to Mitigate NaCl Toxicity.Molecular biotechnology · 2025Article
- An Update of Fungal Endophyte Diversity and Strategies for Augmenting Therapeutic Potential of their Potent Metabolites: Recent Advancement.Applied biochemistry and biotechnology · 2025Review
- Phyllospheric application of Bacillus mucilaginosus mediates the recovery of tea plants exposed to low-temperature stress by alteration of leaf endophytic community and plant physiology.BMC microbiology · 2025Article
- The Changes of the Endophytic Bacterial Community from Pepper Varieties with Different Capsaicinoids.Microorganisms · 2025Article
- Deciphering the endomicrobiome of Podophyllum hexandrum to reveal the endophytic bacterial-association of in-planta podophyllotoxin biosynthesis.World journal of microbiology & biotechnology · 2025Article
- Developing benzylisoquinoline alkaloid-enriched opium poppy via CRISPR-directed genome editing: A review.BMC plant biology · 2024Review
- Arbuscular mycorrhiza and plant growth promoting endophytes facilitates accumulation of saponin under moderate drought stress.Chinese herbal medicines · 2024Article
- Unraveling endophytic diversity in dioecious Siraitia grosvenorii: implications for mogroside production.Applied microbiology and biotechnology · 2024Article
- Unlocking the potential of bacterial endophytes from medicinal plants for drug discovery.Microbial biotechnology · 2024Review
- Promising approaches for simultaneous enhancement of medicinally significant benzylisoquinoline alkaloids in opium poppy.Frontiers in plant science · 2024Review
- Plants and endophytes interaction: a "secret wedlock" for sustainable biosynthesis of pharmaceutically important secondary metabolites.Microbial cell factories · 2023Review
- Endophytes Modulate Plant Genes: Present Status and Future Perspectives.Current microbiology · 2023Review
- Review
- Rhizosphere Fungal Dynamics in Sugarcane during Different Growth Stages.International journal of molecular sciences · 2023Article
- Secondary Metabolites Produced by Plant Growth-Promoting Bacterial Endophytes.Microorganisms · 2022Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MAIN
conclusionEndophytes reside in different parts of the poppy plant and perform the tissue-specific functions. Most leaf endophytes modulate photosynthetic efficiency, plant growth, and productivity while capsule endophytes modulate alkaloid biosynthesis. Endophytes promote plant growth, provide protection from environmental stresses and are the source of important secondary metabolites. Here, we established that the endophytes of opium poppy Papaver somniferum L. may play a role in the modulation of plant productivity and benzylisoquinoline alkaloid (BIA) biosynthesis. A total of 22 endophytes isolated from leaves, roots, capsules and seeds of the poppy plants were identified. Isolated endophytes were used to inoculate the endophytes free poppy seeds and screened for their ability to improve plant productivity and BIA production. It was evident that the endophytes from leaf were involved in improving photosynthetic efficiency, and thus crop growth and yield and the endophytes from capsule were involved in enhancing BIA biosynthesis. Capsule endophytes of alkaloid-rich P. somniferum cv. Sampada enhanced BIA production even in alkaloid-less cv. Sujata. Expression study of the genes involved in BIA biosynthesis conferred the differential regulation of their expression in the presence of capsule endophytes. The capsule endophyte SM1B (Acinetobacter) upregulated the expression of the key genes for the BIA biosynthesis except thebaine 6-O-demethylase (T6ODM) and codeine O-demethylase (CODM). On the other hand, another capsule endophyte SM3B (Marmoricola sp.) could upregulate both T6ODM and CODM. Colonization of poppy plant by endophytes isolated from leaves, roots and capsules found to be higher in their respective plant parts confirmed their tissue-specific role. Overall, the results demonstrate the specific role of endophytes in the modulation of host plant productivity and BIA production.
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Registered trials
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