Evidence map›Paper›PMID 25887356›Full record

ArticleDiabetes care2015

Cardiovascular and All-Cause Mortality Over a 23-Year Period Among Chinese With Newly Diagnosed Diabetes in the Da Qing IGT and Diabetes Study.

Yali An, Ping Zhang, Jinping Wang, Qiuhong Gong, Edward W Gregg, Wenying Yang, Hui Li, Bo Zhang, Ying Shuai, Yanyan Chen and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 105 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Yali AnDepartment of Endocrinology, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Ping ZhangDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA guangwei_li@medmail.com.cn pzhang@cdc.gov.
Jinping WangDepartment of Cardiology, Da Qing First Hospital, Da Qing, China.
Qiuhong GongDepartment of Endocrinology, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Edward W GreggDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA.
Wenying YangDepartment of Endocrinology, China-Japan Friendship Hospital, Beijing, China.
Hui LiDepartment of Cardiology, Da Qing First Hospital, Da Qing, China.
Bo ZhangDepartment of Endocrinology, China-Japan Friendship Hospital, Beijing, China.
Ying ShuaiDepartment of Endocrinology, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Yanyan ChenDepartment of Endocrinology, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Michael M EngelgauCenter for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, Bethesda, MD.
Yiling ChengDivision of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA.
Yinghua HuDepartment of Cardiology, Da Qing First Hospital, Da Qing, China.
Peter H BennettPhoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ.
Guangwei LiDepartment of Endocrinology, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing, China Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China guangwei_li@medmail.com.cn pzhang@cdc.gov.
Centers for Disease Control and Prevention · USFu Wai Hospital · CNChina-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNNational Heart Lung and Blood Institute · USNational Institute of Diabetes and Digestive and Kidney Diseases · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDespite its growing prevalence in China, the extent to which diabetes leads to excess cardiovascular disease (CVD) mortality and all-cause mortality is unclear. RESEARCH DESIGN AND

methodsWe compared death rates and causes of death among 630 people with newly diagnosed diabetes (NDD) and 519 with normal glucose tolerance (NGT) who, in 1986, were identified as a result of screening 110,660 adults aged 25-74 years for diabetes in Da Qing, China.

resultsDuring 23 years of follow-up, 338 (56.5%) participants with NDD and 100 (20.3%) with NGT died. CVD was the predominant cause of death in those with diabetes (47.5% in men and 49.7% in women), almost half of which was due to stroke (52.3% in men and 42.3% in women). The age-standardized incidence of all-cause death was three times as high in those with NDD as in those with NGT with incidences (per 1,000 person-years) of 36.9 (95% CI 31.5-42.3) vs. 13.3 (10.2-16.5) in men (P < 0.0001) and 27.1 (22.9-31.4) vs. 9.2 (7.8-10.6) in women (P < 0.0001). The incidence of CVD deaths in men and women with NDD (17.5 [13.8-21.2] vs. 13.5 [10.5-16.5]) did not differ significantly. Significantly higher death rates attributable to renal disease and infection were also found in the NDD group.

conclusionsDiabetes is associated with a substantially increased risk of death in Chinese adults, especially from CVD, almost half of which is due to stroke.

Indexed as

AdultAgedAsian PeopleCardiovascular DiseasesCause of DeathChinaDiabetes MellitusFemaleFollow-Up StudiesGlucose IntoleranceHumansIncidenceMaleMiddle AgedPrevalence

Identifiers

PMID25887356
PMCPMC4477333
OpenAlexW2079458904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.